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Statements of Stockholders' Equity (USD $)
Total
Accumulated Deficit
Class C Special Shares
Common stock
Balance at beginning of period at Dec. 31, 2008 $ 13,826,419 $ (71,906,660) $ 391 $ 85,732,688
Balance at beginning of period (in shares) at Dec. 31, 2008     65,214 4,507,127
Issuance of common shares        
Stock option expense 1,254,503     1,254,503
Stock warrant expense 64,103     64,103
Registered direct offerings of common shares and warrants, net 11,352,751     11,352,751
Registered direct offerings of common shares and warrants, net (in shares)       1,000,000
Issuance of common shares pursuant to Cell Genesys, Inc. transaction 36,800,043     36,800,043
Issuance of common shares pursuant to Cell Genesys, Inc. transaction (in shares)       3,369,967
Credit equity financing facility 60,343     60,343
Net loss (47,527,768) (47,527,768)    
Balance at end of period at Dec. 31, 2009 15,830,394 (119,434,428) 391 135,264,431
Balance at end of period (in shares) at Dec. 31, 2009     65,214 8,877,094
Issuance of common shares        
Stock option exercise 2,014     2,014
Stock option exercise (in shares)       222
Stock option expense 992,757     992,757
Stock warrant expense 65,529     65,529
Registered direct offerings of common shares and warrants, net 48,452,644     48,452,644
Registered direct offerings of common shares and warrants, net (in shares)       4,687,871
June 1, 2012 Fractional Share Adjustment       1
Net loss (46,196,216) (46,196,216)    
Balance at end of period at Dec. 31, 2010 19,147,122 (165,630,644) 391 184,777,375
Balance at end of period (in shares) at Dec. 31, 2010     65,214 13,565,188
Balance at beginning of period at Dec. 29, 2010        
Issuance of common shares        
Registered direct offerings of common shares and warrants, net (in shares)       1,764,706
Balance at end of period at Dec. 31, 2010 19,147,122 (165,630,644) 391 184,777,375
Balance at end of period (in shares) at Dec. 31, 2010     65,214 13,565,188
Issuance of common shares        
Stock option exercise 32,442     32,442
Stock option exercise (in shares)       3,194
Warrant exercises - various 24,062     24,062
Warrant exercises - various (in shares)       1,458
Stock option expense 1,177,683     1,177,683
Stock warrant expense 204,980     204,980
Underwritten offering of common shares, net 44,961,137     44,961,137
Underwritten offering of common shares, net (in shares)       2,666,666
Registered direct offerings of common shares and warrants, net 23,876,370     23,876,370
Registered direct offerings of common shares and warrants, net (in shares)       2,033,247
June 1, 2012 Fractional Share Adjustment       1
Net loss (51,608,504) (51,608,504)    
Balance at end of period at Dec. 31, 2011 $ 37,815,292 $ (217,239,148) $ 391 $ 255,054,049
Balance at end of period (in shares) at Dec. 31, 2011     65,214 18,269,754