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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 M1TEhYfJjkDJeiqgHBUMqMW/epKz/t8GbtQDXAUnQOcZX1R6Eid1HkHv1VOCz8Yn
 vbGoMggXCYElbqAX77soGQ==

<SEC-DOCUMENT>0001144204-08-021541.txt : 20080410
<SEC-HEADER>0001144204-08-021541.hdr.sgml : 20080410
<ACCEPTANCE-DATETIME>20080410141928
ACCESSION NUMBER:		0001144204-08-021541
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20071017
FILED AS OF DATE:		20080410
DATE AS OF CHANGE:		20080410

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Advaxis, Inc.
		CENTRAL INDEX KEY:			0001100397
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				841521955
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1031

	BUSINESS ADDRESS:	
		STREET 1:		675 ROUTE 1
		STREET 2:		SUITE B 113
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902
		BUSINESS PHONE:		732 545 1590

	MAIL ADDRESS:	
		STREET 1:		675 ROUTE 1
		STREET 2:		SUITE B 113
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GREAT EXPECTATIONS & ASSOCIATES INC
		DATE OF NAME CHANGE:	19991203

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MCKEARN THOMAS J
		CENTRAL INDEX KEY:			0001022849

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-28489
		FILM NUMBER:		08749653

	BUSINESS ADDRESS:	
		STREET 1:		CO/CYTOGEN CORPORATION
		STREET 2:		600 COLLEGE ROAD EAST
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540
		BUSINESS PHONE:		6099878230

	MAIL ADDRESS:	
		STREET 1:		CO/CYTOGEN CORPORATION
		STREET 2:		600 COLLEGE RD
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			19044
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>v110293_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-10-17</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001100397</issuerCik>
        <issuerName>Advaxis, Inc.</issuerName>
        <issuerTradingSymbol>ADXS</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001022849</rptOwnerCik>
            <rptOwnerName>MCKEARN THOMAS J</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ADVAXIS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>TECHNOLOGY CENTER OF NJ, 675 US HWY ONE</rptOwnerStreet2>
            <rptOwnerCity>NORTH BRUNSWICK</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08902</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Warrant</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.40</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2007-10-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>D</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>90549</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2004-11-12</value>
            </exerciseDate>
            <expirationDate>
                <value>2009-11-12</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>90549</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>22274</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Warrant</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.274</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2007-10-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>131969</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2004-11-12</value>
            </exerciseDate>
            <expirationDate>
                <value>2009-11-12</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>131969</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>154243</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The two reported transactions involved an anti-dilution adjustment of an outstanding warrant, resulting in the deemed
 cancellation of the &quot;old&quot; warrant and the deemed grant of a replacement warrant. The adjustment was necessary because the
 anti-dilution provision in the &quot;old&quot; warrant was triggered by a subsequent warrant issuance by the Issuer, resulting in a
 new exercise price and a change in the amount of shares underlying the warrants.</footnote>
        <footnote id="F2">This total includes 22,274 shares of common stock issuable upon the exercise of warrants as previously reported with the
 Securities and Exchange Commission on November 16, 2004.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Thomas McKearn</signatureName>
        <signatureDate>2008-04-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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