CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
Operating activities
Net loss	$ (45,255)	$ (45,476)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	2,336	2,298
Stock-based compensation	17,033	13,306
Non-cash operating lease cost	1,061	1,009
Changes in valuation of warrant investment	(485)
(Gain) loss on sale of available-for-sale securities	(28)	256
Unrealized gain on investments	(242)
Non-cash interest expense	780	358
Foreign currency remeasurement loss (gain)	386	(524)
Changes in operating assets and liabilities:
Accounts receivable	(1,688)	553
Inventories	(12,130)	(75)
Other assets	2,009	89
Accounts payable	2,497	(2,703)
Accrued liabilities and other non-current liabilities	859	(1,992)
Deferred product revenue	167	(9)
Net cash used in operating activities	(32,700)	(32,910)
Investing activities
Capital expenditures	(446)	(1,149)
Purchases of investments	(2,132)	(94,028)
Proceeds from maturities and sale of investments	55,556	38,017
Net cash provided by (used in) investing activities	52,978	(57,160)
Financing activities
Net proceeds from equity incentives	5,085	6,984
Net (offering costs) proceeds from public offerings	(359)	76,547
Net proceeds (payments) on revolving line of credit	1,470	(35)
Proceeds from loans	15,000
Contribution from noncontrolling interest	1,000
Net cash provided by financing activities	22,196	83,496
Effect of exchange rates on cash, cash equivalents, and restricted cash	(639)	625
Net increase (decrease) in cash, cash equivalents and restricted cash	41,835	(5,949)
Cash, cash equivalents and restricted cash, beginning of period	38,903	37,421
Cash, cash equivalents and restricted cash, end of period	$ 80,738	$ 31,472