Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2019

Accounting Policies [Abstract]

Summary of Product Revenue by Geographical Locations of Customers

Product revenue by geographical locations of customers during the three and six months ended June 30, 2019 and 2018, were as follows (in thousands):

	Three Months Ended				Six Months Ended
	June 30,				June 30,
	2019		2018		2019		2018
Product revenue:
Europe, Middle East and Africa	$	12,748	$	12,018	$	25,400	$	23,024
North America		5,158		3,149		9,709		5,536
Other		303		253		604		424
Total product revenue	$	18,209	$	15,420	$	35,713	$	28,984

Anti-Dilutive Effect of Common Shares

The table below presents potential shares that were excluded from the calculation of the weighted average number of shares outstanding used for the calculation of diluted net loss per share. These are excluded from the calculation due to their anti-dilutive effect for the three and six months ended June 30, 2019 and 2018 (shares in thousands):

	Three Months Ended				Six Months Ended
	June 30,				June 30,
	2019		2018		2019		2018
Weighted average number of anti-dilutive potential shares:
Stock options		17,691		18,631		17,670		18,259
Restricted stock units		2,897		2,024		2,578		1,803
Employee stock purchase plan rights		—		171		—		157
Total		20,588		20,826		20,248		20,219