CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 22,560	$ 71,018
Short-term investments	45,116	25,698
Investment in marketable equity securities	3,952	11,163
Accounts receivable	6,868	5,794
Inventories	12,531	10,812
Prepaid expenses	1,274	1,166
Other current assets	1,804	4,755
Total current assets	94,105	130,406
Non-current assets:
Property and equipment, net	2,985	3,549
Goodwill	1,316	1,316
Intangible assets, net	738	940
Restricted cash	184	612
Other assets	4,148	2,579
Total assets	103,476	139,402
Current liabilities:
Accounts payable	8,587	5,217
Accrued liabilities	11,218	9,853
Manufacturing and development obligations - current		3,282
Debt - current	6,934	2,956
Deferred product revenue - current	149	554
Total current liabilities	26,888	21,862
Non-current liabilities:
Debt - non-current	12,441	16,848
Deferred income taxes	150	122
Manufacturing and development obligations - non-current	4,770	4,542
Other non-current liabilities	1,440	1,263
Total liabilities	45,689	44,637
Commitments and contingencies
Stockholders' equity:
Preferred stock, $0.001 par value; 5,000 shares authorized, issuable in series; zero shares issued and outstanding at December 31, 2016 and 2015, respectively
Common stock, $0.001 par value; 225,000 shares authorized; 103,475 and 99,095 shares issued and outstanding at December 31, 2016 and 2015, respectively	103	99
Additional paid-in capital	718,299	685,189
Accumulated other comprehensive income	103	7,289
Accumulated deficit	(660,718)	(597,812)
Total stockholders' equity	57,787	94,765
Total liabilities and stockholders' equity	$ 103,476	$ 139,402