Significant Components of Deferred Tax Assets (Detail) (USD $) In Thousands, unless otherwise specified	Dec. 31, 2012	Dec. 31, 2011
Deferred tax assets:
Net operating loss carryforwards	$ 137,700	$ 137,800
Research and development credit carryforwards	30,800	31,400
Capitalized inventory costs	900	500
Inventory reserve	700	200
Capitalized research and development	9,100	10,300
Capitalized intangible asset	100	0
Deferred compensation	4,800	4,200
Accrued liabilities	100	400
Depreciation	1,300	1,400
Acqusition costs	200	200
Deferred tenant allowance	200	200
Capital loss carryforwards	3,900	3,900
Total deferred tax assets	190,500	191,300
Valuation allowance	(190,500)	(191,300)
Net deferred tax assets	0	0
Deferred tax liabilities:
Amortization of goodwill	62	0
Total deferred tax liabilities	62	0
Trademarks
Deferred tax assets:
Capitalized intangible asset	400	200
Capitalized Revenue Sharing Rights
Deferred tax assets:
Capitalized intangible asset	$ 300	$ 600