CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Product related:
Product revenue	$ 36,695	$ 30,602	$ 21,677
Cost of product revenue	20,616	18,535	12,046
Gross profit on product revenue	16,079	12,067	9,631
Government grants and cooperative agreements revenue	91	2,442	1,432
Operating expenses:
Research and development	7,603	7,178	5,195
Selling, general and administrative	25,665	23,053	21,577
Amortization of intangible assets	202	202	67
Acquisition related costs net of gain on non-controlling equity interest	0	0	182
Total operating expenses	33,470	30,433	27,021
Loss from operations	(17,300)	(15,924)	(15,958)
Non-operating income (expense), net:
Revaluation of warrant liability	2,059	486	39
Foreign exchange gain (loss)	86	(529)	(816)
Interest expense	(551)	(964)	(689)
Other income, net	31	92	607
Total non-operating income (expense), net	1,625	(915)	(859)
Loss before income taxes	(15,675)	(16,839)	(16,817)
Provision for income taxes	242	143	94
Net loss	$ (15,917)	$ (16,982)	$ (16,911)
Net loss per common share:
Basic	$ (0.29)	$ (0.35)	$ (0.42)
Diluted	$ (0.33)	$ (0.35)	$ (0.42)
Weighted average common shares outstanding used for calculating net loss per common share:
Basic	54,515	48,050	40,300
Diluted	55,061	48,050	40,300