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Difference Between Provision for Income Taxes and Amounts Computed by Applying Federal Statutory Income Tax Rate to Loss before Taxes (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]      
Federal statutory tax $ (8,891) $ (11,352) $ (12,510)
Federal research credits 1,874 (2,159) (1,630)
State research credits (822) (767) (749)
Expiration of federal carryovers 4,858 4,651 9,200
Change in valuation allowance 6,379 10,482 6,738
Compensation related items 1,794 460 978
State taxes (1,127) (1,294) (1,921)
Other 171 298 178
Provision for income taxes $ 488 $ 319 $ 284