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Summary of Significant Accounting Policies (Tables)
9 Months Ended
Sep. 30, 2022
Accounting Policies [Abstract]  
Summary of Product Revenue by Geographical Locations of Customers

Product revenue by geographical locations of customers during the three and nine months ended September 30, 2022 and 2021, was as follows (in thousands):

 

 

Three Months Ended

 

 

Nine Months Ended

 

 

 

September 30,

 

 

September 30,

 

 

 

2022

 

 

2021

 

 

2022

 

 

2021

 

Product revenue:

 

 

 

 

 

 

 

 

 

 

 

 

North America

 

$

26,079

 

 

$

20,860

 

 

$

73,856

 

 

$

45,171

 

Europe, Middle East and Africa

 

 

13,115

 

 

 

14,965

 

 

 

42,815

 

 

 

44,473

 

Other

 

 

377

 

 

 

306

 

 

 

1,343

 

 

 

1,350

 

Total product revenue

 

$

39,571

 

 

$

36,131

 

 

$

118,014

 

 

$

90,994

 

 

Anti-Dilutive Effect of Common Shares

The table below presents potential shares that were excluded from the calculation of the weighted average number of shares outstanding used for the calculation of diluted net loss per share. These are excluded from the calculation due to their anti-dilutive effect for the three and nine months ended September 30, 2022 and 2021 (shares in thousands):

 

 

 

Three Months Ended

 

 

Nine Months Ended

 

 

 

September 30,

 

 

September 30,

 

 

 

2022

 

 

2021

 

 

2022

 

 

2021

 

Weighted average number of anti-dilutive potential shares:

 

 

 

 

 

 

 

 

 

 

 

 

Stock options

 

 

16,265

 

 

 

16,362

 

 

 

16,109

 

 

 

16,626

 

Restricted stock units

 

 

7,982

 

 

 

6,763

 

 

 

7,606

 

 

 

6,642

 

Employee stock purchase plan rights

 

 

144

 

 

 

34

 

 

 

230

 

 

 

123

 

Total

 

 

24,391

 

 

 

23,159

 

 

 

23,945

 

 

 

23,391