X0306 4 2022-07-26 0001018399 ENTERPRISE BANCORP INC /MA/ EBTC 0001637827 GALLAGHER MICHAEL JOHN C/O ENTERPRISE BANCORP, INC. 222 MERRIMACK STREET LOWELL MA 01852 1 EVP-Principal Subsidiary Common Stock 9579.0479 I By Trust Common Stock 2744.5712 D Stock Option (Right to Buy) 20.29 2022-07-26 4 M 0 400 D 2018-03-18 2024-03-17 Common Stock 400 13 D Option (Right to Buy) 21.86 2022-07-26 4 M 0 320 D 2020-03-15 2026-03-14 Common Stock 320 202 D Exercise of an option. /s/ John P. Clancy, Jr. as attorney-in-fact for Michael John Gallagher 2022-07-28