Exhibit

We consent to the incorporation by reference in the Registration Statement (No. 333-213799, 333-184089, 333-159006, 333-136700) on Form S-8 and (No. 333-219879) on Form S-3/A of Enterprise Bancorp, Inc. of our report dated March 13, 2018, relating to the consolidated financial statements and the effectiveness of internal control over financial reporting of Enterprise Bancorp, Inc., appearing in this Annual Report on Form 10-K of Enterprise Bancorp, Inc. for the year ended December 31, 2017.