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Financial Instruments (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives $ 50   $ 50   $ 178
Derivatives not designated as hedging instruments, Asset Derivatives 61   61   75
Derivatives designated as hedging instruments, Liability Derivatives 118   118   18
Derivatives not designated as hedging instruments, Liability Derivatives 96   96   60
Four Quarter Rolling Average of Notional Amount of Foreign Exchange Contracts Hedging Foreign Currency Transactions 20,500   $ 20,500   19,100
Description of Net Investment Hedge Activity     We have approximately €4.95 billion of euro-denominated long-term debt and €750 million of euro-denominated commercial paper borrowings outstanding, which qualify as a net investment hedge against our investments in European businesses. As of June 30, 2018, the net investment hedge is deemed to be effective.    
Gain (loss) recorded in Accumulated other comprehensive loss (245) $ 66 $ (200) $ 130  
(Gain) loss reclassified from Accumulated other comprehensive loss into Product Sales (effective portion) (1) 5 $ (28) 10  
Maximum Length of Time, Foreign Currency Cash Flow Hedge     4 years 22 days    
Gain recognized in Other income, net 19 $ 28 $ 70 $ 40  
Foreign Currency Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months (33)   (33)    
Other Current Assets [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives 23   23   77
Derivatives not designated as hedging instruments, Asset Derivatives 39   39   70
Other Noncurrent Assets [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives 27   27   101
Derivatives not designated as hedging instruments, Asset Derivatives 22   22   5
Accrued Liabilities [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Liability Derivatives 43   43   10
Derivatives not designated as hedging instruments, Liability Derivatives 93   93   57
Other Long-term Liabilities [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Liability Derivatives 75   75   8
Derivatives not designated as hedging instruments, Liability Derivatives $ 3   $ 3   $ 3