X0202 3 2006-01-25 0 0001017813 PATIENT INFOSYSTEMS INC PATY 0001335280 LUBIN DANIEL C RADIUS VENTURE PARTNERS LLC 400 MADISON AVE 8TH FLOOR NEW YORK NY 10017 1 0 0 0 Common Stock 6431776 I By Fund Common Stock 216710 I By Fund through escrow Common Stock 92929 I By Fund through escrow Call Option Equivalent (obligation to sell) 0 2006-01-25 2007-07-25 Common Stock 92929 I By Fund through escrow Shares are owned of record by Radius Venture Partners I, L.P. Mr. Lubin, who has been designated to become one of the Issuer's directors, is a managing member of Radius Venture Partners, L.L.C., the general partner of Radius Venture Partners I, L.P. and therefore may be deemed to beneficially own the securities owned by Radius Venture Partners I, L.P. Mr. Lubin disclaims ownership of the reported securities except to the extent of his pecuniary interest therein. The reported number of shares represents the minimum number of shares issuable to Radius Venture Partners I, L.P. upon termination of the escrow arrangement and liquidation of the escrow account. In the event that the Reporting Person acquires a greater number of shares upon termination of the escrow agreement and liquidation of the escrow account, the Reporting Person will file a Form 4 reflecting the acquisition of additional shares. Shares are beneficially owned by Radius Venture Partners I, L.P. Represents shares held in escrow for the benefit of former stockholders of CCS Consolidated, Inc. whose shares were converted into shares of the Issuer as a result of a merger between CCS Consolidated, Inc. and the Issuer. Shares are beneficially owned by Radius Venture Partners I, L.P. Represents shares held in escrow for the benefit of another stockholder of the Issuer. The number of shares to be released to the other stockholder is contingent upon the occurrence of certain events as described in a letter agreement between the Issuer and the other stockholder. The reported number of shares represents the maximum number of shares issuable to Radius Venture Partners I, L.P. upon termination of the escrow arrangement and liquidation of the escrow account. These shares are subject to a call option in favor of the other stockholder as described in footnote (5). Another stockholder of the Issuer may, contingent upon the occurrence of certain events not in the control of Radius Venture Partners I, L.P. or the other stockholder, acquire the entire amount of the stock held in escrow as described in footnote (4), including the shares reported by Radius Venture Partners I, L.P. No additional consideration will be received by Radius Venture Partners I, L.P. to the extent the call option on these shares is exercised by the other stockholder. To the extent that the shares held in escrow may not be distributed to the other stockholder, the Reporting Person will report the partial or full expiration of the call option on Form 4. /s/Daniel C. Lubin 2006-02-06