X0202 3 2006-01-25 0 0001017813 PATIENT INFOSYSTEMS INC PATY 0001351470 PATERSON CHRIS E C/O PATIENT INFOSYSTEMS, INC. 12301 NW 39TH STREET CORAL SPRINGS FL 33065 0 1 0 0 President and CEO No securities beneficially owned 0 D Employee Stock Option (right to purchase) 0.0234 2006-01-25 2015-04-18 Common Stock 1017666 D Of the shares subject to this option, 1/4th are vested and the remaining shares vest in accordance with the following schedule: 1/36th of the remaining shares vest monthly beginning on February 25, 2006. /s/Chris E. Paterson 2006-02-03