8-K

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): September 19, 2006

CAREGUIDE, INC.

(Exact name of the Registrant as specified in its charter)

Delaware	0-22319	16-1476509
(State or other jurisdiction of incorporation)	(Commission File Number)	(IRS Employer Identification No.)

12301 N.W. 39^th Street
Coral Springs, Florida 33065

(Address of principal executive offices and Zip Code)

the Registrant’s telephone number, including area code: (954) 796-3714

Patient Infosystems, Inc.

(Former name or former address, if changed since last report.)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the Registrant under any of the following provisions:

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Item 5.03 Amendments to Articles of Incorporation of Bylaws; Change in Fiscal Year

          Effective September 19, 2006, the registrant changed its corporate name from Patient Infosystems, Inc. to CareGuide, Inc. (the “Company”). On September 25, 2006, the Company’s common stock began trading on the NASD Over-the-Counter Bulletin Board under the symbol CGDE.

          The Company effected the corporate name change by filing a Certificate of Amendment to its Certificate of Incorporation with the Secretary of State of the State of Delaware, the form of which was previously filed as Appendix A to its Information Statement on Schedule 14C filed with the Securities and Exchange Commission on August 28, 2006.

          A copy of the press release dated September 25, 2006 announcing the change of the trading symbol is attached hereto as Exhibit 99.1.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

Exhibit
Number	Exhibit Description
3.1	Certificate of Amendment to Certificate of Incorporation (incorporated by reference to Appendix A to Schedule 14C filed on August 28, 2006).
99.1	Press Release, dated September 25, 2006, “CareGuide to Begin Trading under Symbol CGDE Immediately.”

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SIGNATURES

          Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Date: September 25, 2006	CareGuide, Inc.
	By:	/s/ Chris E. Paterson
		Chris E. Paterson
		President and Chief Executive Officer

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EXHIBIT INDEX

Exhibit
Number	Exhibit Description
3.1	Certificate of Amendment to Certificate of Incorporation (incorporated by reference to Appendix A to Schedule 14C filed on August 28, 2006).
99.1	Press Release, dated September 25, 2006, “CareGuide to Begin Trading under Symbol CGDE Immediately.”

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EX-99.1

Exhibit 99.1

Contact: Chris Paterson
Chief Executive Officer
(954) 796-3651
cpaterson@careguide.com

CAREGUIDE TO BEGIN TRADING UNDER SYMBOL CGDE IMMEDIATELY

Coral Springs, Florida (September 25, 2006) — CareGuide, Inc. (OTCBB: CGDE), a national disease and healthcare management company, today announced that it will begin trading today on the Over-the-Counter Bulletin Board under ticker symbol “CGDE.” Previously, the Company had traded under the name Patient Infosystems, Inc., d/b/a CareGuide, and under the symbol PATY.

“We are pleased to announce the change of our ticker symbol to CGDE,” said Chris E. Paterson, president and chief executive officer of CareGuide. “We believe the new ticker symbol more properly reflects the recent change of the Company’s legal name to CareGuide, Inc.”

Headquartered in Coral Springs, Florida, CareGuide is a national disease and care management company serving the health and benefit plans of managed care organizations, employers, unions, third party administrators and government customers. Understanding that health status is dynamic and encompasses physical, mental and social qualities, CareGuide focuses on total population health management. The Company employs a unique scientific approach to identify members of health plans who are at risk for medical destabilization and high claims expense. Through flexible, evidence-based and member-centric interventions that are matched to the individual’s holistic health needs, hospital admissions are prevented and quality of life is enhanced. CareGuide distinguishes itself by combining high human touch with technology to assist chronically ill members in self-managing their health. Visit www.careguide.com for more information.

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