Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities
Net loss	$ (54,877)	$ (38,789)
Adjustments to reconcile net loss to net cash used in operating activities
Stock-based compensation expense	4,166	2,599
Change in fair value of warrant liability	(192)	750
Change in fair value of convertible notes payable	2,477
Research and development expense - license amendment	841
Gain on forgiveness of note payable		(147)
Net loss on extinguishment of convertible debt		2,387
Amortization of debt discount		1,582
Changes in operating assets and liabilities
Prepaid expenses and other current assets	(5,103)	(2,230)
Accounts payable	4,259	1,514
Accrued expenses	289	1,803
Derivative liability	(1,174)
Licenses payable	800	(125)
Net cash used in operating activities	(48,514)	(30,656)
Cash flows (used in) provided by financing activities
Payment of convertible note		(13,551)
Proceeds from issuance of common stock, net of issuance costs		97,957
Proceeds from exercise of warrants		7,252
Proceeds from issuance of common stock in at-the-market offering	457
Payment of at-the-market offering issuance costs	(273)
Proceeds from exercise of options	8	65
Proceeds from sales of common stock under ESPP	99	104
Net cash provided by financing activities	291	91,827
Net (decrease) increase in cash	(48,223)	61,171
Cash, beginning of period	78,734	15,662
Cash, end of period	30,511	76,833
Supplemental disclosure of cash flow information:
Cash paid for interest	11	10
Cash paid for income taxes
Non-cash investing and financing activities:
Reclass of warrant liabilities related to Series A warrants exercised for cash		1,155
Right-of-use assets obtained in exchange for operating lease liabilities		75
Issuance of common stock for convertible notes		69
Issuance of common stock for license payable	840
At-the-market offering issuance costs, accrued but not paid	32
Issuance of common stock for settlement of debt		1,377
Extinguishment of beneficial conversion feature		$ 1,519