Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows from operating activities
Net loss	$ (35,273)	$ (27,974)
Adjustments to reconcile net loss to net cash used in operating activities
Stock-based compensation expense	3,193	1,742
Change in fair value of warrant liability	(283)	826
Change in fair value of convertible notes payable	340
Research and development expense - license amendment	841
Gain on forgiveness of note payable		(147)
Net loss on extinguishment of convertible debt		2,387
Amortization of debt discount		1,564
Changes in operating assets and liabilities
Prepaid expenses and other current assets	(6,363)	(1,214)
Accounts payable	613	(849)
Accrued expenses	(134)	644
Derivative liability	(1,174)
Licenses payable	(800)	2,875
Net cash used in operating activities	(37,440)	(20,146)
Cash flows (used in) provided by financing activities
Payment of convertible note		(13,620)
Proceeds from issuance of common stock, net of issuance costs		97,957
Proceeds from exercise of warrants		7,252
Payment of deferred offering costs	(126)
Proceeds from exercise of options	8	65
Proceeds from sales of common stock under ESPP	75	30
Net cash (used in) provided by financing activities	(43)	91,684
Net (decrease) increase in cash	(37,483)	71,538
Cash, beginning of period	78,734	15,662
Cash, end of period	41,251	87,200
Supplemental disclosure of cash flow information:
Cash paid for interest	9	8
Cash paid for income taxes
Non-cash investing and financing activities:
Reclass of warrant liabilities related to Series A warrants exercised for cash		1,155
Right-of-use assets obtained in exchange for operating lease liabilities		75
Issuance of common stock for convertible notes		40
Issuance of common stock for license payable	840
Deferred offering costs, accrued but not paid	127
Issuance of common stock for settlement of debt		1,377
Extinguishment of beneficial conversion feature		$ 1,519