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Consolidated Statements of Changes in Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Common Stock [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
Total
Beginning balance, value at Dec. 31, 2019 $ 27 $ 56,027 $ (56,061) $ (7)
Common Stock, Shares, Outstanding, Beginning Balance at Dec. 31, 2019 27,028,533      
Stock-based compensation expense 2,044 2,044
Issuance of common stock for prepaid services 330 330
[custom:IssuanceOfCommonStockForPrepaidServicesShares] 400,000      
Issuance of common stock for license acquired $ 2 2,441 2,443
Issuance of common stock, net of issuance costs $ 15 8,835 8,850
Issuance of common stock for license acquired, shares 1,809,845      
Issuance of common stock, net of issuance costs, shares 15,166,666      
Net Income (Loss) Attributable to Parent (19,101) (19,101)
Warrants exercised for cash 169 $ 169
Common Stock, Shares, Outstanding, Ending Balance at Dec. 31, 2020 54,535,891     54,535,891
Issuance of common stock and warrants, pursuant to September 2020 Securities Purchase Agreement, net of issuance costs 8,865,000      
Issuance of common stock and warrants, pursuant to Securities Purchase Agreement, net of issuance costs, shares 1,112,219      
Warrants exercised for cash, shares 153,628      
Issuance of common stock and warrants, pursuant to     Securities Purchase Agreement, net of issuance costs $ 1 1,378 $ 1,379
Issuance of common stock and warrants, pursuant to     September 2020 Securities Purchase Agreement,     net of issuance costs 9 6,356 6,365
Net loss (19,101) (19,101)
Ending balance, value at Dec. 31, 2020 54 77,680 (75,162) 2,572
Stock-based compensation expense 8,347 8,347
Issuance of common stock, options exercised 102 102
Issuance of common stock, options exercised, shares 79,138      
Issuance of common stock for license acquired $ 3 4,830 4,832
Issuance of common stock for settlement of debt 1,377 1,377
Issuance of common stock, net of issuance costs $ 40 97,917 97,957
Issuance of common stock for license acquired, shares 2,570,266      
Issuance of common stock, net of issuance costs, shares 39,788,554      
Net Income (Loss) Attributable to Parent (66,048) (66,048)
Warrants exercised for cash $ 7 8,401 $ 8,408
Common Stock, Shares, Outstanding, Ending Balance at Dec. 31, 2021 105,500,445     105,500,445
custom:IssuanceOfCommonStockPursuantTo2021SecuritiesPurchaseAgreement 540,147      
[custom:IssuanceOfCommonStockForConversionOfDebtShares] 69,065      
[custom:IssuanceOfCommonStockForExtinguishmentOfDebtShares] 406,250      
Warrants exercised for cash, shares 7,431,125      
Net loss (66,048) $ (66,048)
Extinguishment of beneficial conversion feature (1,519) (1,519)
Issuance of common stock for conversion of debt 138 138
Issuance of common stock, ESPP 104 104
Issuance of common stock, ESPP, shares 80,009      
Issuance of common stock, pursuant to 2021     Securities Purchase Agreements $ 1 1,051 1,052
Ending balance, value at Dec. 31, 2021 $ 105 $ 198,428 $ (141,210) $ 57,323