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Consolidated Statements of Changes in Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Common Stock
Additional Paid-in Capital
Accumulated Deficit
Total
Beginning balance (in shares) at Dec. 31, 2018 3,081,546      
Beginning balance at Dec. 31, 2018 $ 3 $ 97 $ (4,806) $ (4,706)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Stock-based compensation expense $ 0 459 0 459
Issuance of common stock and warrants in a private offering, net of $16.5 million warrant liability, shares 1,829,407      
Issuance of common stock and warrants in a private offering, net of $16.5 million warrant liability $ 2 0 0 2
Effect of reverse merger, shares 947,218      
Effect of reverse merger $ (1) (300) 0 (299)
Issuance of common stock for license acquired, shares 992,782      
Issuance of common stock for license acquired $ 1 2,999 0 3,000
Warrants exercised for cash (in shares) 14,332,620      
Warrants exercised for cash $ 14 4,503 0 4,517
Reclass of warrant liabilites related to Series A warrants exercised for cash, shares 0      
Reclass of warrant liabilites related to Series A warrants exercised for cash $ 0 5,600 0 5,600
Reclass of Series B warrants from warrant liability to stockholders' equity, shares 0      
Reclass of Series B warrants from warrant liability to stockholders' equity $ 0 31,473 0 31,473
Issuance of common stock for conversion of debt and accrued interest, shares 172,284      
Issuance of common stock for conversion of debt and accrued interest $ 0 2,715 9 2,715
Issuance of common stock and warrants, pursuant to Securities Purchase Agreement, net of issuance costs, shares 4,475,000      
Issuance of common stock and warrants, pursuant to Securities Purchase Agreement, net of issuance costs $ 5 5,915 0 5,920
Issuance of common stock in at-the-market offering, net of issuance costs, shares 1,197,676      
Issuance of common stock in at-the-market offering, net of issuance costs $ 1 2,566 0 2,567
Net loss $ 0 0 (51,255) (51,255)
Ending balance (in shares) at Dec. 31, 2019 27,028,533      
Ending balance at Dec. 31, 2019 $ 27 56,027 (56,061) (7)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Stock-based compensation expense $ 0 2,044 0 2,044
Issuance of common stock for prepaid services, shares 400,000      
Issuance of common stock for prepaid services $ 0 330 0 330
Issuance of common stock for license acquired, shares 1,809,845      
Issuance of common stock for license acquired $ 2 2,441 0 0
Issuance of common stock, net of issuance costs, shares 15,166,666      
Issuance of common stock, net of issuance costs $ 15 8,835 0 8,850
Warrants exercised for cash (in shares) 153,628      
Warrants exercised for cash $ 0 169 0 169
Reclass of Series B warrants from warrant liability to stockholders' equity       0
Issuance of common stock and warrants, pursuant to Securities Purchase Agreement, net of issuance costs, shares 1,112,219      
Issuance of common stock and warrants, pursuant to Securities Purchase Agreement, net of issuance costs $ 1 1,378 0 1,379
Beneficial conversion feature of convertible debt, shares 0      
Beneficial conversion feature of convertible debt $ 0 100 0 100
Issuance of common stock and warrants, pursuant to September 2020 Securities Purchase Agreement, net of issuance costs, shares 8,865,000      
Issuance of common stock and warrants, pursuant to September 2020 Securities Purchase Agreement, net of issuance costs $ 9 6,356 0 6,365
Net loss $ 0 0 (19,101) (19,101)
Ending balance (in shares) at Dec. 31, 2020 54,535,891      
Ending balance at Dec. 31, 2020 $ 54 $ 77,680 $ (75,162) $ 2,572