Organization and Summary of Significant Accounting Policies - Liquidity (Details) $ / shares in Units, $ in Thousands						1 Months Ended		12 Months Ended		27 Months Ended
	Sep. 20, 2018 USD ($) $ / shares shares	Apr. 02, 2018 USD ($) warrant $ / shares shares	Sep. 10, 2017 USD ($) $ / shares shares	Apr. 26, 2017 USD ($) $ / shares shares	Jul. 05, 2016 shares	Sep. 30, 2016 USD ($) $ / shares shares	Jan. 31, 2016 shares	Dec. 31, 2018 USD ($) $ / shares shares	Dec. 31, 2017 USD ($) shares	Sep. 30, 2018 shares	Apr. 30, 2018 $ / shares	Apr. 20, 2017 $ / shares	Dec. 31, 2016 USD ($)
Basis Of Presentation [Line Items]
Accumulated deficit | $								$ 325,229	$ 315,987
Working capital | $								4,100
Net loss | $								(9,242)	321
Net cash used in operating activities | $								(8,126)	(10,571)
Cash | $								3,579	6,331
Cash and cash equivalents | $								$ 3,579	$ 6,331				$ 2,087
Shares issuable upon exercise of warrants (in shares)								437,000
Common stock, authorized (in shares)								60,000,000	30,000,000
Maximum potential proceeds from divestiture | $									$ 12,700
Proceeds from sale of rights to Vitaros product line | $									11,500
Proceeds from sale of product related inventory | $									709
Payment recognized related to transition services | $									500
Repayments of debt | $									$ 6,600
Shelf registration statement, available amount | $								$ 95,200
Entity public float, primary public offerings of securities, threshold (less than) | $								$ 75,000
Percent of public float eligible to to be raised if under threshold (as a percent)								33.33%
September 2018 Financing [Member]
Basis Of Presentation [Line Items]
Net proceeds from sale of common stock and warrants after transaction costs | $	$ 1,100
September 2017 Financing [Member]
Basis Of Presentation [Line Items]
Net proceeds from sale of common stock and warrants after transaction costs | $			$ 3,100
April 2017 Financing [Member]
Basis Of Presentation [Line Items]
Sale of stock, price per share (in usd per share) | $ / shares				$ 1.40
September 2016 Financing [Member]
Basis Of Presentation [Line Items]
Net proceeds from sale of common stock and warrants after transaction costs | $						$ 3,200
Common Stock
Basis Of Presentation [Line Items]
Issuance of common stock (in shares)							8,428
Common Stock | September 2018 Financing [Member]
Basis Of Presentation [Line Items]
Issuance of common stock (in shares)	153,333
Shares issued, price per share (in usd per share) | $ / shares	$ 8.10
Common Stock | April 2018 Financing [Member]
Basis Of Presentation [Line Items]
Net proceeds from financing transaction | $		$ 2,900
Number of units sold in transaction (in shares)		7,100,000
Sale of stock, price per share (in usd per share) | $ / shares		$ 0.50
Common Stock | September 2017 Financing [Member]
Basis Of Presentation [Line Items]
Issuance of common stock (in shares)			2,136,614
Shares issued, price per share (in usd per share) | $ / shares			$ 1.73
Common Stock | April 2017 Financing [Member]
Basis Of Presentation [Line Items]
Net proceeds from financing transaction | $				$ 5,900
Number of securities called by each warrant (in shares)				0.75
Common Stock | September 2016 Financing [Member]
Basis Of Presentation [Line Items]
Issuance of common stock (in shares)						1,082,402
Shares issued, price per share (in usd per share) | $ / shares						$ 3.45
September 2018 Warrants, Tranche 1 [Member] | September 2018 Financing [Member]
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)	3,450,000
Warrant vesting period	6 months
Exercise price (in usd per share) | $ / shares	$ 0.30
September 2018 Warrants [Member] | September 2018 Financing [Member]
Basis Of Presentation [Line Items]
Warrant expiration period	5 years
September 2018 Warrants, Tranche 2 [Member] | September 2018 Financing [Member]
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)	2,677,160
Warrant vesting period	6 months
Exercise price (in usd per share) | $ / shares	$ 0.40
September 2018 Placement Agent Warrants [Member] | September 2018 Financing [Member]
Basis Of Presentation [Line Items]
Warrant vesting period	6 months
Exercise price (in usd per share) | $ / shares	$ 0.3375
Warrant expiration period	5 years
April 2018 Placement Agent Warrants [Member] | April 2018 Financing [Member]
Basis Of Presentation [Line Items]
Exercise price (in usd per share) | $ / shares		$ 0.625
Warrant expiration period		5 years
April 2018 Warrants [Member] | April 2018 Financing [Member]
Basis Of Presentation [Line Items]
Exercise price (in usd per share) | $ / shares		$ 0.50
Warrant expiration period		5 years
Number of warrants attached to each stock unit (in warrants) | warrant		1
Number of securities called by each warrant (in shares)		0.5
Warrants Expiring March 2020, Tranche 2
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								13,000
Exercise price (in usd per share) | $ / shares								$ 18.00
Warrants Expiring March 2020, Tranche 2 | September 2017 Financing [Member]
Basis Of Presentation [Line Items]
Exercise price (in usd per share) | $ / shares			$ 2.16								$ 0.60
Warrant expiration period			2 years 6 months
Warrants Expiring March 2020, Tranche 1 [Member] | September 2017 Financing [Member]
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)			1,068,307
Exercise price (in usd per share) | $ / shares			$ 1.67								$ 0.60
Warrant expiration period			2 years 6 months
Underwriter Warrants 2017 [Member] | April 2017 Financing [Member]
Basis Of Presentation [Line Items]
Exercise price (in usd per share) | $ / shares				$ 1.75
Warrant expiration period				5 years
April 2017 Warrants [Member] | April 2017 Financing [Member]
Basis Of Presentation [Line Items]
Exercise price (in usd per share) | $ / shares				$ 1.55
Warrant expiration period				5 years
Placement Agent Warrants [Member] | September 2016 Financing [Member]
Basis Of Presentation [Line Items]
Exercise price (in usd per share) | $ / shares						$ 4.3125
Warrant expiration period						5 years
Private Placement Warrants [Member] | September 2016 Financing [Member]
Basis Of Presentation [Line Items]
Warrant expiration period						5 years 6 months
Warrants Expiring October 2024
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								1,000
Exercise price (in usd per share) | $ / shares								$ 387.00
Warrants Expiring April 2022
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								8,000
Exercise price (in usd per share) | $ / shares								$ 52.50
Warrants Expiring March 2024 Tranche 3
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								89,000
Exercise price (in usd per share) | $ / shares								$ 12.00
Warrants Expiring July 2025
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								1,000
Exercise price (in usd per share) | $ / shares								$ 492.00
Warrants Expiring May 2022
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								82,000
Exercise price (in usd per share) | $ / shares								$ 46.50
Warrants Expiring May 2023
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								80,000
Exercise price (in usd per share) | $ / shares								$ 15.00
Warrants Expiring March 2023, Tranche 2
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								4,000
Exercise price (in usd per share) | $ / shares								$ 21.30
Warrants Expiring January 2023
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								11,000
Exercise price (in usd per share) | $ / shares								$ 12.60
Warrants Expiring March 2023
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								11,000
Exercise price (in usd per share) | $ / shares								$ 12.60
Warrants Expiring January 2023, Tranche 2
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								3,000
Exercise price (in usd per share) | $ / shares								$ 21.30
Warrants Expiring March 2024 Tranche 2
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								115,000
Exercise price (in usd per share) | $ / shares								$ 9.00
Warrants Expiring March 2024
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								8,000
Exercise price (in usd per share) | $ / shares								$ 10.14
Warrants Expiring March 2023, Tranche 3
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)								12,000
Exercise price (in usd per share) | $ / shares								$ 18.90
Private Placement And Placement Agent Warrants [Member] | April 2017 Warrant Amendment [Member]
Basis Of Presentation [Line Items]
Exercise price (in usd per share) | $ / shares												$ 1.55
HC Wainwright [Member] | Common Stock | April 2017 Financing [Member]
Basis Of Presentation [Line Items]
Number of units sold in transaction (in shares)				5,030,000
HC Wainwright [Member] | September 2018 Placement Agent Warrants [Member] | September 2018 Financing [Member]
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)	230,000
HC Wainwright [Member] | April 2018 Placement Agent Warrants [Member] | April 2018 Financing [Member]
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)		355,000
HC Wainwright [Member] | Warrants Expiring March 2020, Tranche 2 | September 2017 Financing [Member]
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)			106,831
HC Wainwright [Member] | Underwriter Warrants 2017 [Member] | April 2017 Financing [Member]
Basis Of Presentation [Line Items]
Shares issuable upon exercise of warrants (in shares)				251,500
Aspire Capital Fund, LLC [Member]
Basis Of Presentation [Line Items]
Issuance of common stock (in shares)					253,165					500,000