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Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2018
Equity [Abstract]  
Summary of Warrant Activity

A summary of warrant activity during the year ended December 31, 2018 is as follows (share amounts in thousands):

          Weighted
    Common Shares     Average
    Issuable upon     Exercise
    Exercise     Price
Outstanding at December 31, 2017   236    $ 117.30 
     Issued   342    $ 12.30 
     Exercised   (35)   $ 44.40 
     Cancelled   (107)   $ 119.70 
Outstanding as of December 31, 2018   437    $ 20.70 
Exercisable as of December 31, 2018   225    $ 30.30 

 

The following table shows the number of outstanding warrants by exercise price and date of expiration as of December 31, 2018 (share amounts in thousands):

Shares Issuable Upon Exercise     Exercise Price   Expiration Date
13    $ 18.00    March 2020
8    $ 52.50    April 2022
82    $ 46.50    May 2022
11    $ 12.60    January 2023
3    $ 21.30    January 2023
11    $ 12.60    March 2023
4    $ 21.30    March 2023
12    $ 18.90    March 2023
80    $ 15.00    May 2023
8    $ 10.14    March 2024
115    $ 9.00    March 2024
89    $ 12.00    March 2024
1    $ 387.00    October 2024
1    $ 492.00    July 2025
437