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Organization and Summary of Significant Accounting Policies - Liquidity (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended
Sep. 10, 2017
USD ($)
$ / shares
shares
Apr. 26, 2017
USD ($)
$ / shares
shares
Mar. 08, 2017
USD ($)
Apr. 30, 2017
USD ($)
Oct. 31, 2016
Jan. 31, 2016
$ / shares
shares
Sep. 30, 2017
USD ($)
$ / shares
shares
Sep. 30, 2016
USD ($)
Mar. 31, 2016
USD ($)
Sep. 30, 2017
USD ($)
$ / shares
shares
Sep. 30, 2017
USD ($)
$ / shares
shares
Sep. 30, 2016
USD ($)
Apr. 20, 2017
$ / shares
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Feb. 28, 2015
$ / shares
Oct. 17, 2014
$ / shares
shares
Aug. 25, 2014
USD ($)
Basis Of Presentation [Line Items]                                    
Accumulated deficit             $ (313,541)     $ (313,541) $ (313,541)     $ (316,308)        
Working capital             6,900     6,900 6,900              
Net income             (3,832) $ (1,291)     2,767 $ (7,134)            
Cash             $ 8,463 $ 5,614   $ 8,463 $ 8,463 $ 5,614   $ 2,087 $ 3,887      
Net proceeds from sale of common stock and warrants after transaction costs                 $ 9,600                  
Shares issuable upon exercise (in shares) | shares             7,270,070     7,270,070 7,270,070              
Maximum potential proceeds from divestiture     $ 12,700                              
Proceeds from sale of rights to Vitaros product line     11,500                              
Proceeds from sale of product related inventory       $ 709                            
Payment recognized related to transition services                   $ 500                
Shelf registration statement, available amount             $ 100,000     100,000 $ 100,000             $ 100,000
Entity public float, primary public offerings of securities, threshold (less than)             $ 75,000     $ 75,000 $ 75,000              
Percent of public float eligible to to be raised if under threshold (as a percent)             33.33%     33.33% 33.33%              
Reverse stock split, conversion ratio (as a percent)         0.1                          
Loan and Security Agreement                                    
Basis Of Presentation [Line Items]                                    
Repayments of debt     $ 6,600                              
September 2017 Warrants                                    
Basis Of Presentation [Line Items]                                    
Shares issuable upon exercise (in shares) | shares             1,068,307     1,068,307 1,068,307              
Exercise price (in usd per share) | $ / shares             $ 1.67     $ 1.67 $ 1.67              
September 2017 Placement Agent Warrants                                    
Basis Of Presentation [Line Items]                                    
Shares issuable upon exercise (in shares) | shares             106,831     106,831 106,831              
Exercise price (in usd per share) | $ / shares             $ 2.16     $ 2.16 $ 2.16              
Common Stock                                    
Basis Of Presentation [Line Items]                                    
Exercise price (in usd per share) | $ / shares           $ 8.80                   $ 18.20    
Number of securities called by each warrant (in shares) | shares           0.5                        
September 2017 Financing                                    
Basis Of Presentation [Line Items]                                    
Net proceeds from sale of common stock and warrants after transaction costs $ 3,100                                  
September 2017 Financing | September 2017 Warrants                                    
Basis Of Presentation [Line Items]                                    
Shares issuable upon exercise (in shares) | shares 1,068,307                                  
Exercise price (in usd per share) | $ / shares $ 1.67                                  
Date from which warrants are exercisable Sep. 13, 2017                                  
Warrant expiration period 2 years 6 months                                  
September 2017 Financing | September 2017 Placement Agent Warrants                                    
Basis Of Presentation [Line Items]                                    
Exercise price (in usd per share) | $ / shares $ 2.16                                  
Warrant expiration period 2 years 6 months                                  
September 2017 Financing | H.C. Wainwright | September 2017 Placement Agent Warrants                                    
Basis Of Presentation [Line Items]                                    
Shares issuable upon exercise (in shares) | shares 106,831                                  
April 2017 Financing                                    
Basis Of Presentation [Line Items]                                    
Exercise price (in usd per share) | $ / shares   $ 1.55                                
Warrant expiration period   5 years                                
Sale of stock, price per share (in usd per share) | $ / shares   $ 1.40                                
April 2017 Financing | Underwriter Warrants                                    
Basis Of Presentation [Line Items]                                    
Exercise price (in usd per share) | $ / shares   $ 1.75                                
Warrant expiration period   5 years                                
April 2017 Warrant Amendment | Private Placement And Placement Agent Warrants                                    
Basis Of Presentation [Line Items]                                    
Exercise price (in usd per share) | $ / shares                         $ 1.55          
Common Stock                                    
Basis Of Presentation [Line Items]                                    
Issuance of common stock (in shares) | shares           252,842                        
Common Stock | Loan and Security Agreement                                    
Basis Of Presentation [Line Items]                                    
Shares issuable upon exercise (in shares) | shares                                 19,380  
Exercise price (in usd per share) | $ / shares                                 $ 12.90  
Common Stock | September 2017 Financing                                    
Basis Of Presentation [Line Items]                                    
Issuance of common stock (in shares) | shares 2,136,614                                  
Shares issued, price per share (in usd per share) | $ / shares $ 1.73                                  
Common Stock | April 2017 Financing                                    
Basis Of Presentation [Line Items]                                    
Net proceeds from financing transaction   $ 5,900                                
Number of securities called by each warrant (in shares) | shares   0.75                                
Common Stock | April 2017 Financing | H.C. Wainwright                                    
Basis Of Presentation [Line Items]                                    
Number of units sold in transaction (in shares) | shares   5,030,000                                
Common Stock | April 2017 Financing | H.C. Wainwright | Underwriter Warrants                                    
Basis Of Presentation [Line Items]                                    
Shares issuable upon exercise (in shares) | shares   251,500