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Stockholders' Equity (Tables)
9 Months Ended
Sep. 30, 2017
Equity [Abstract]  
Summary of Warrant Activity
A summary of warrant activity during the nine months ended September 30, 2017 is as follows:
 
Common Shares
Issuable upon
Exercise
 
Weighted
Average
Exercise
Price
Outstanding at December 31, 2016
2,317,846

 
$
15.19

Issued
5,199,138

 
$
1.60

Cancelled
(246,914
)
 
52.50

Outstanding as of September 30, 2017
7,270,070

 
$
3.85

Exercisable as of September 30, 2017
7,270,070

 
$
3.85


The following table shows the number of outstanding warrants by exercise price and date of expiration as of September 30, 2017:
Shares Issuable Upon Exercise
 
Exercise Price
 
Expiration Date
300,000

 
$
34.00

 
May 2018
1,068,307

 
$
1.67

 
March 2020
106,831

 
$
2.16

 
March 2020
251,500

 
$
1.75

 
April 2022
4,638,425

 
$
1.55

 
May 2022
428,620

 
$
8.80

 
January 2023
441,763

 
$
8.80

 
March 2023
19,380

 
$
12.90

 
October 2024
15,244

 
$
16.40

 
July 2025
7,270,070