<SEC-DOCUMENT>0001017491-17-000124-index.html : 20171102
<SEC-HEADER>0001017491-17-000124.hdr.sgml : 20171102
<ACCEPTANCE-DATETIME>20171102160722
ACCESSION NUMBER:		0001017491-17-000124
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20171102
DATE AS OF CHANGE:		20171102

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			APRICUS BIOSCIENCES, INC.
		CENTRAL INDEX KEY:			0001017491
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				870449967
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-221285
		FILM NUMBER:		171172332

	BUSINESS ADDRESS:	
		STREET 1:		11975 EL CAMINO REAL,
		STREET 2:		SUITE 300
		CITY:			SAN DIEGO,
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		(858) 222-8041

	MAIL ADDRESS:	
		STREET 1:		11975 EL CAMINO REAL,
		STREET 2:		SUITE 300
		CITY:			SAN DIEGO,
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NEXMED INC
		DATE OF NAME CHANGE:	19970311
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>apriuniversals-32017.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: apriuniversals-32017.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.13
<SEQUENCE>2
<FILENAME>exhibit413formofindenture-.htm
<DESCRIPTION>EXHIBIT 4.13
<TEXT>
Document 2 - file: exhibit413formofindenture-.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>exhibit51legalopinion2017u.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 3 - file: exhibit51legalopinion2017u.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>4
<FILENAME>ex231bdoconsentuniversals-3.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 4 - file: ex231bdoconsentuniversals-3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>apricuslogoa02a.jpg
<TEXT>
Document 5 - file: apricuslogoa02a.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>brownsteinletterhead2.jpg
<TEXT>
Document 6 - file: brownsteinletterhead2.jpg

</DOCUMENT>
</SEC-DOCUMENT>