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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2015
Income Tax Disclosure [Abstract]  
Deferred Tax Assets
Deferred tax assets consist of the following:
 
 
December 31,
 
 
2015
 
2014
Net operating tax loss and capital loss carryforwards
 
$
65,783

 
$
60,380

Capitalized research and development costs
 
2,890

 

Research and development tax credits
 
950

 
534

Deferred compensation
 
106

 
168

Other accruals and reserves
 
1,092

 
670

Basis of intangible assets
 
4,197

 
4,610

Total deferred tax asset
 
75,018

 
66,362

Less valuation allowance
 
(75,018
)
 
(66,362
)
Net deferred tax asset
 
$

 
$

Reconciliation of Unrecognized Tax Benefits
A reconciliation of the Company’s unrecognized tax benefits from January 1, 2015 through December 31, 2015 is provided in the following table (in thousands):
 
 
Year Ended December 31,
 
 
2015
 
2014
Beginning balance
 
$
2,822

 
$
2,795

Change in current period positions
 
56

 
34

Change in prior period positions
 
4

 
(7
)
Ending balance
 
$
2,882

 
$
2,822

Reconciliation of Income Taxes
The reconciliation of income taxes computed using the statutory United States income tax rate and the provision (benefit) for income taxes for continuing operations for the years ended December 31, 2015, 2014, and 2013, are as follows:
 
 
Year Ended December 31,
 
 
2015
 
2014
 
2013
Federal statutory tax rate
 
(34
)%
 
(34
)%
 
(34
)%
State taxes, net of federal benefit
 
 %
 
(1
)%
 
(1
)%
Valuation allowance
 
45
 %
 
22
 %
 
37
 %
Prior year true-ups
 
(1
)%
 
17
 %
 
1
 %
Revaluation of warrants
 
(6
)%
 
 %
 
 %
Permanent differences
 
(2
)%
 
(3
)%
 
(1
)%
Tax credits
 
(2
)%
 
(1
)%
 
(2
)%
Income tax expense
 
 %
 
 %
 
 %