X0306 4 2022-06-29 0 0001802768 Royalty Pharma plc RPRX 0001016835 RIGGS RORY B C/O ROYALTY PHARMA PLC 110 E. 59TH STREET NEW YORK NY 10022 1 0 0 0 Class A Ordinary Shares 2022-06-29 4 S 0 30000 42.1746 D 421712 D Class A Ordinary Shares 85187 I By New Ventures III LLC Class A Ordinary Shares 15000 I By Spouse The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $42.05 to $42.29 per share. The holder undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. /s/ Jason Mehar, as Attorney-in-Fact for Rory B. Riggs 2022-06-29