Common Stock and Warrants (Details Narrative) - USD ($)													1 Months Ended								12 Months Ended
	Feb. 12, 2018	Feb. 11, 2018	Feb. 10, 2018	Feb. 03, 2018	Dec. 06, 2017	Mar. 01, 2017	Feb. 10, 2017	Feb. 02, 2017	Jan. 10, 2017	Dec. 06, 2016	Feb. 02, 2016	Aug. 05, 2015	Feb. 22, 2019	Nov. 26, 2018	Feb. 22, 2018	Feb. 13, 2018	Oct. 16, 2017	Jul. 21, 2017	Jun. 28, 2017	Feb. 17, 2017	Dec. 31, 2018	Dec. 31, 2017	Jul. 12, 2018	Jul. 12, 2017	Dec. 31, 2016	Sep. 09, 2016	Jul. 12, 2016	Dec. 31, 2015	Jul. 12, 2015	Jul. 12, 2014	Nov. 29, 2013
Common stock, par value																					$ 0.00001	$ 0.00001
Common stock, Authorized																					500,000,000	500,000,000
Common stock, shares Issued																					87,175,522	76,145,418
Common stock, shares outstanding																					87,175,522	76,145,418
Estimated volatility																					108.00%
Risk free interest rate																					2.97%
Expected dividend rate																					0.00%	0.00%
Expected life																					9 years
Common stock shares reserved under stock option plan																						102,582
Subscription Agreement
Private placement offering description														Company entered into Subscription Agreements (each, a “Subscription Agreement”) with KCC, a private corporation owning in excess of 10% of the Company's issued and outstanding common stock, for the purchase and sale of 10,335,000 units of the Company's equity securities (the “Units”) at a price of $1.50 per Unit, pursuant to a private placement offering conducted by the Company (the “Offering”) for (i) aggregate cash proceeds of $14,407,500 and (ii) conversion of $1,095,000 principal amount of outstanding loan indebtedness. The Each Unit consists of: (i) one (1) share of common stock; and (ii) one (1) Series I Stock Purchase Warrant to purchase one (1) share of common stock at a price of $2.00 per share for a period of seven (7) years commencing on the date the Warrants are first issued. (the “Series I Warrants”). The Series I Warrants do not have a cashless exercise provision. KCC does not have any registration rights with respect to the shares comprising a part of the Units or issuable upon exercise of the Series I Warrants. A deemed dividend of $180,000 was incurred with respect to the difference between the floor price of the conversion feature of $395,000 of outstanding loan indebtedness. This amount is a reclassification within equity only.
Private Placement [Member] | Common Stock
Fair value of the common stock																	$ 1,309,458	$ 634,782
KCC [Member] | Series F Warrant [Member]
Proceeds from issuance of common stock																			$ 344,624
KCC [Member] | Private Placement [Member]
Common stock shares reserved under stock option plan																		410,000
Series A [Member]
Weighted Average Exercise Price																					$ 0.35	$ 0.35
Series A [Member] | Dr. Gerlach [Member]
Warrant exercised												240,000													1,200,000
Issuance of common stock												196,812
Weighted Average Exercise Price																									$ 0.35
Warrant vest five equal installments																							240,000	240,000			240,000		240,000	240,000
Series D [Member]
Warrant exercised																100,000
Weighted Average Exercise Price																					1.10	1.10			$ 1.10
Proceeds from issuance of common stock																$ 110,000
Series D [Member] | On June 5, 2015 [Member]
Warrant exercised										100,000																		1,010,000
Weighted Average Exercise Price																												$ 1.10
Proceeds from issuance of common stock					$ 110,000					$ 110,000
Series A Warrant [Member] | Dr. Gerlach [Member]
Warrant exercised				480,000					240,000
Issuance of common stock				457,480					204,571
Common stock shares reserved under stock option plan	480,000								240,000
Debt conversion converted instrument shares issued	457,480								204,571
SeriesHWarrantMember | Private Placement [Member]
Weighted Average Exercise Price																	$ 2.75
Estimated volatility																	98.25%
Market price of common stock																	$ 3.10
Risk free interest rate																	1.95%
Expected dividend rate																	0.00%
Expected life																	5 years
SeriesHWarrantMember | Private Placement [Member] | Self-directed offering [Member]
Maturity period																	5 years
SeriesGWarrantMember | Private Placement [Member]
Estimated volatility																		102.23%
Market price of common stock																		$ 2.92
Risk free interest rate																		1.81%
Expected dividend rate																		0.00%
Expected life																		5 years
SeriesGWarrantMember | Private Placement [Member] | Self-directed offering [Member]
Weighted Average Exercise Price																		$ 2.68
Maturity period																		5 years
Number of equity securities offered under the plan, shares																		460,250
Share price																		$ 2.44
Number of equity securities offered under the plan, amount																		$ 1,122,610
Fair value of the common stock																		$ 487,828
Series F [Member]
Weighted Average Exercise Price																					3.45	$ 3.45
Series F [Member] | KCC [Member]
Warrant exercised																			114,493
Issuance of common stock																			114,493
Weighted Average Exercise Price																			$ 3.01
Proceeds from issuance of common stock																			$ 344,624
Series F [Member] | Joe Sierchio [Member]
Warrant exercised															7,246
Issuance of common stock													4,899
Series F Warrant [Member] | February 2017 loan agreements [Member]
Warrant exercised																						128,985
Series C [Member]
Warrant exercised																															3,500,000
Weighted Average Exercise Price																						$ 0.49									$ 0.49
Series B [Member]
Warrant exercised																															3,500,000
Weighted Average Exercise Price											$ 0.46											0.46									$ 0.46
Proceeds from issuance of common stock								$ 1,000,000
Series H [Member]
Weighted Average Exercise Price																					2.75	2.75
Series H [Member] | Private Placement [Member] | Self-directed offering [Member]
Weighted Average Exercise Price																	$ 2.75
Number of equity securities offered under the plan, shares																	920,000
Share price																	$ 2.50
Number of equity securities offered under the plan, amount																	$ 2,300,000
Fair value of the common stock																	$ 990,542
Series H [Member] | Joe Sierchio [Member]
Warrant exercised															10,000
Issuance of common stock													7,418
Series G [Member]
Weighted Average Exercise Price																					2.68	2.68
Series E [Member]
Warrant exercised																										584,416
Weighted Average Exercise Price																					$ 1.54	$ 1.54
Series D Warrant [Member]
Weighted Average Exercise Price																$ 1.10
Proceeds from issuance of common stock																$ 110,000
Debt conversion converted instrument shares issued																100,000
Kenneth Kirkland [Member]
Debt conversion converted instrument shares issued															41,033
Kenneth Kirkland [Member] | Equity Option [Member]
Common stock shares reserved under stock option plan								40,000							50,000
Debt conversion converted instrument shares issued								29,642							41,033
Kenneth Kirkland [Member] | Equity Option [Member]
Warrant exercised								40,000
Issuance of common stock								29,642
KCC [Member] | Series B Warrant [Member]
Warrant exercised						1,326,087
Issuance of common stock						1,181,194					2,173,913
Proceeds from issuance of common stock											$ 1,000,000
KCC [Member] | Series C Warrant [Member]
Warrant exercised						3,500,000
Issuance of common stock						3,092,637
KCC [Member] | Series B and C warrants [Member]
Issuance of common stock						4,273,831
KCC [Member] | Series F Warrant [Member]
Proceeds from issuance of common stock																			$ 344,624
Joseph Sierchio [Member]
Debt conversion converted instrument shares issued															22,711
Joseph Sierchio [Member] | Series F [Member]
Common stock shares reserved under stock option plan															7,246
Debt conversion converted instrument shares issued															4,899
Joseph Sierchio [Member] | Series H [Member]
Common stock shares reserved under stock option plan															10,000
Debt conversion converted instrument shares issued															7,418
Joseph Sierchio [Member] | Equity Option [Member]
Common stock shares reserved under stock option plan							70,000
Debt conversion converted instrument shares issued			38,642
Joseph Sierchio [Member] | Equity Option [Member]
Warrant exercised							70,000
Issuance of common stock							38,642
Thomas bold [Member]
Common stock shares reserved under stock option plan				60,000
Debt conversion converted instrument shares issued				44,083
Thomas bold [Member] | Equity Option [Member]
Issuance of common stock																				34,296
Consultant [Member]
Common stock shares reserved under stock option plan		40,000
Debt conversion converted instrument shares issued		17,480
Dr. Gerlach [Member] | Series A [Member]
Common stock shares reserved under stock option plan	480,000
Debt conversion converted instrument shares issued	457,480