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Debt (Details Narrative) - USD ($)
1 Months Ended 12 Months Ended
Mar. 09, 2017
Sep. 09, 2016
Nov. 26, 2018
Dec. 31, 2018
Dec. 31, 2017
Feb. 12, 2018
Feb. 03, 2018
Oct. 19, 2017
Jul. 27, 2017
May 11, 2017
Feb. 23, 2017
Feb. 17, 2017
Jan. 10, 2017
Interest expense       $ 76,831 $ 77,284                
Common stock shares reserved under stock option plan         102,582                
Estimated volatility       108.00%                  
Risk free interest rate       2.97%                  
Expected dividend rate       0.00% 0.00%                
Expected life       9 years                  
Debt discount       $ 58,438 $ 919,367                
Kenneth Kirkland [Member]                          
Common stock shares reserved under stock option plan       50,000 50,000                
Joseph Sierchio [Member]                          
Common stock shares reserved under stock option plan       50,000 50,000         75,000      
Thomas bold [Member]                          
Common stock shares reserved under stock option plan             60,000            
Thomas bold [Member] | Chief Financial Officer [Member]                          
Common stock shares reserved under stock option plan                       40,000  
Loan agreement [Member] | KCC [Member]                          
Interest expense       $ 49,680 $ 51,385                
Accretion of debt discount       $ 0 $ 534,519                
Convertible debt financing, Maximum amount   $ 900,000                      
Interest rate   7.00%                 7.00%    
Convertible debt financing, Loan received   $ 700,000                 $ 395,000    
Convertible debt financing, Remaining amount   $ 200,000                      
Debt instrument terms conversion feature   The Note became convertible, at KCC’s sole discretion, into shares of our common stock at conversion rate equal to the lesser of: (i) $1.54, the closing price of our common stock on the day prior to the issuance of the Note or (ii) a 20% discount to the average closing price of our common stock for the five days prior to the date on which KCC elects to convert the Note, subject to a floor price of $1.23 per share.     The maturity date of the KCC February Note was extended from February 23, 2018 to December 31, 2019.                
Exercise Price         $ 1.25                
Market price of common stock         $ 1.54                
Estimated volatility         92.30%                
Risk free interest rate         1.23%                
Expected dividend rate         0.00%                
Expected life         5 years                
Fair value         $ 340,735                
Beneficial conversion featture amount         359,265                
Debt discount         $ 700,000                
Period for accretion of discount         1 year 2 months 30 days                
Loan agreement [Member] | Joseph Sierchio [Member]                          
Interest rate                     7.00%    
Convertible debt financing, Loan received                     $ 25,000    
February 2017 Loan Agreements [member] | KCC [Member]                          
Interest rate 7.00%                        
Convertible debt financing, Loan received $ 395,000                        
February 2017 Loan Agreements [member] | KCC [Member] | Sierchio and Investor [Member]                          
Interest rate 7.00%                        
Convertible debt financing, Loan received $ 25,000                        
Debt instrument terms conversion feature (i) $3.45, the closing price of the Company’s common stock on the day prior to the issuance of the February 2017 Notes or (ii) a 20% discount to the average closing price of the Company’s common stock for the five days prior to the date on which the Holder(s) elect to convert the February 2017 Note(s), subject to a floor price of $2.76.                        
Series I [Member]                          
Exercise Price       $ 2.00                  
Series I [Member] | September 9, 2016 Loan Agreements 2 [Member] | KCC [Member]                          
Debt instrument terms conversion feature     KCC and the Company entered into an Amendment No. 2 to the February 2017 Note whereby the principal amount was settled by the issuance of 463,333 units of the Company’s equity securities (the “Units”) at a price of $1.50 per Unit. The Unit price represents a discount of $0.03 from the closing price on November 23, 2018 and a $0.05 discount to the 20-day lookback of the closing price of the Company's common stock as quoted on the OTC Markets Pink Sheets for the 20 trading days prior to the Closing Date. Each Unit consists of: (i) one (1) share of common stock; and (ii) one (1) Series I Stock Purchase Warrant to purchase one (1) share of common stock at a price of $2.00 per share for a period of seven (7) years commencing on the date the Warrants are first issued. (the “Series I Warrants”).                    
Series I [Member] | February 2017 Loan Agreements 2 [Member] | KCC [Member]                          
Debt instrument terms conversion feature     KCC and the Company entered into an Amendment No. 2 to the February 2017 Note whereby the principal amount was settled by the issuance of 296,667 units of the Company’s equity securities (the “Units”) at a price of $1.50 per Unit. Each Unit consists of: (i) one (1) share of common stock; and (ii) one (1) Series I Stock Purchase Warrant to purchase one (1) share of common stock at a price of $2.00 per share for a period of seven (7) years commencing on the date the Warrants are first issued. (the “Series I Warrants”).                    
Series E Warrant [Member] | Loan agreement [Member] | KCC [Member]                          
Common stock shares reserved under stock option plan   584,416                      
Debt instrument terms conversion feature   Common stock at a purchase price of the lesser of: (i) $1.54, the closing price of the Company’s common stock on the day prior to issuance of the Series E Warrant; or (ii) a 20% discount to the average closing price of the Company’s common stock for the five days prior to the date on which KCC elects to exercise the Series E Warrant.                      
Series F Warrant [Member] | February 2017 Loan Agreements [member]                          
Interest expense       $ 27,151                  
Accretion of debt discount       $ 58,438                  
Exercise Price         $ 3.45                
Principal amount         $ 420,000                
Market price of common stock         $ 3.53                
Estimated volatility         110.00%                
Risk free interest rate         2.13%                
Expected dividend rate         0.00%                
Expected life         5 years                
Fair value         $ 211,073                
Beneficial conversion featture amount         232,213                
Debt discount         $ 443,286                
Period for accretion of discount         1 year 2 months 30 days                
Series F Warrant [Member] | February 2017 Loan Agreements [member] | Sierchio [Member]                          
Repaid of note principal               $ 25,000          
Accrued interest               $ 1,149          
Common stock shares reserved under stock option plan 7,246                        
Series F Warrant [Member] | February 2017 Loan Agreements [member] | Investor [Member]                          
Repaid of note principal                 $ 25,000        
Accrued interest                 $ 676        
Common stock shares reserved under stock option plan 7,246                        
Series F Warrant [Member] | February 2017 Loan Agreements [member] | KCC [Member]                          
Common stock shares reserved under stock option plan 114,493                        
Series F Warrant [Member] | February 2017 Loan Agreements [member] | KCC [Member] | Sierchio and Investor [Member]                          
Debt instrument terms conversion feature : (i) $3.45, the closing price of the Company’s common stock on the day prior to issuance of the Series F Warrant; or (ii) a 20% discount to the average closing price of the Company’s common stock for the five days prior to the date on which the Holder elects to exercise their Series F Warrant.                        
Series F Warrant [Member] | February 2017 Loan Agreements 1 [Member]                          
Exercise Price         $ 2.90                
Principal amount         $ 25,000                
Market price of common stock         $ 2.90                
Estimated volatility         116.00%                
Risk free interest rate         1.87%                
Expected dividend rate         0.00%                
Series A Warrant [Member] | Dr. Gerlach [Member]                          
Common stock shares reserved under stock option plan           480,000             240,000