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Debt (Details Narrative) - USD ($)
12 Months Ended
Mar. 09, 2017
Sep. 09, 2016
Dec. 31, 2017
Dec. 31, 2016
Oct. 19, 2017
Jul. 27, 2017
Feb. 23, 2017
Interest expense     $ 77,284 $ 15,220      
Accretion of debt discount     $ (919,367) $ (165,481)      
Common stock shares reserved under stock option plan     102,582        
Estimated volatility       92.00%      
Loan agreement [Member] | KCC [Member]              
Interest expense     $ 51,385 $ 15,220      
Accretion of debt discount     $ 534,519 $ 165,481      
Convertible debt financing, Maximum amount   $ 900,000          
Interest rate   7.00%         7.00%
Convertible debt financing, Loan received   $ 700,000         $ 395,000
Convertible debt financing, Remaining amount   $ 200,000          
Debt instrument terms conversion feature  

The Note became convertible, at KCC’s sole discretion, into shares of our common stock at conversion rate equal to the lesser of: (i) $1.54, the closing price of our common stock on the day prior to the issuance of the Note or (ii) a 20% discount to the average closing price of our common stock for the five days prior to the date on which KCC elects to convert the Note, subject to a floor price of $1.23 per share.

The maturity date of the KCC February Note was extended from February 23, 2018 to December 31, 2019.

       
Exercise Price     $ 1.25        
Market price of common stock     $ 1.54        
Estimated volatility     92.30%        
Risk free interest rate     1.23%        
Expected dividend rate     0.00%        
Expected life     5 years        
Fair value     $ 340,735        
Beneficial conversion featture amount     359,265        
Debt discount     $ 700,000        
Period for accretion of discount     1 year 2 months 30 days        
February 2017 Loan Agreements [member] | KCC [Member]              
Interest rate 7.00%            
Convertible debt financing, Loan received $ 395,000            
Series E Warrant [Member] | Loan agreement [Member] | KCC [Member]              
Common stock shares reserved under stock option plan   584,416          
Debt instrument terms conversion feature  

Common stock at a purchase price of the lesser of: (i) $1.54, the closing price of the Company’s common stock on the day prior to issuance of the Series E Warrant; or (ii) a 20% discount to the average closing price of the Company’s common stock for the five days prior to the date on which KCC elects to exercise the Series E Warrant.

         
Series F Warrant [Member] | February 2017 Loan Agreements [member]              
Interest expense     $ 25,899        
Accretion of debt discount     384,848        
Remaining debt discount     $ 58,438        
Exercise Price     $ 3.45        
Principal amount     $ 420,000        
Market price of common stock     $ 3.53        
Estimated volatility     110.00%        
Risk free interest rate     2.13%        
Expected dividend rate     0.00%        
Expected life     5 years        
Fair value     $ 211,073        
Beneficial conversion featture amount     232,213        
Debt discount     $ 443,286        
Period for accretion of discount     1 year 2 months 30 days        
Series F Warrant [Member] | February 2017 Loan Agreements [member] | KCC [Member]              
Common stock shares reserved under stock option plan 114,493            
Series F Warrant [Member] | February 2017 Loan Agreements 1 [Member]              
Exercise Price     $ 2.90        
Principal amount     $ 25,000        
Market price of common stock     $ 3.80        
Estimated volatility     116.00%        
Risk free interest rate     1.87%        
Expected dividend rate     0.00%        
Investor [Member] | Series F Warrant [Member] | February 2017 Loan Agreements [member]              
Repaid of note principal           $ 25,000  
Accrued interest           $ 676  
Common stock shares reserved under stock option plan 7,246            
Sierchio [Member] | Series F Warrant [Member] | February 2017 Loan Agreements [member]              
Repaid of note principal         $ 25,000    
Accrued interest         $ 1,149    
Common stock shares reserved under stock option plan 7,246            
Sierchio and Investor [Member] | February 2017 Loan Agreements [member] | KCC [Member]              
Interest rate 7.00%            
Convertible debt financing, Loan received $ 25,000            
Debt instrument terms conversion feature

(i) $3.45, the closing price of the Company’s common stock on the day prior to the issuance of the February 2017 Notes or (ii) a 20% discount to the average closing price of the Company’s common stock for the five days prior to the date on which the Holder(s) elect to convert the February 2017 Note(s), subject to a floor price of $2.76.

           
Sierchio and Investor [Member] | Series F Warrant [Member] | February 2017 Loan Agreements [member] | KCC [Member]              
Debt instrument terms conversion feature

(i) $3.45, the closing price of the Company’s common stock on the day prior to issuance of the Series F Warrant; or (ii) a 20% discount to the average closing price of the Company’s common stock for the five days prior to the date on which the Holder elects to exercise their Series F Warrant.