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Equity (Tables)
3 Months Ended
Mar. 31, 2022
Equity [Abstract]  
Schedule of warrants outstanding
                  
   Shares of Common Stock Issuable from
Warrants Outstanding as of
  Weighted   
   March 31,  December 31,  Average   
Description  2022  2021  Exercise Price  Expiration
Series F   -    7,246   $3.45   February 23, 2022 & March 9, 2022
Series G   460,250    460,250   $2.68   July 21, 2022
Series H   910,000    910,000   $2.75   October 16, 2022
Series I   10,335,000    10,335,000   $2.00   November 26, 2025
Total   11,705,250    12,296,912         
Schedule of stock option activity
                    
   Number of
Options
  Weighted
Average
Exercise
Price ($)
  Weighted
Average
Remaining
Contractual
Term
(years)
  Aggregate
Intrinsic
Value ($)
Outstanding at December 31, 2020   5,895,570    2.45           
Granted   50,000    1.72           
Forfeited   (2,805,571)   2.74           
Outstanding at September 30, 2021   3,139,999    2.17           
Forfeited   (40,000)   1.79           
Outstanding at March 31, 2022   3,099,999    2.17    4.30    - 
Vested and exercisable at March 31, 2022   2,699,999    2.02    4.30    - 
Condensed Income Statement [Table Text Block]
          
   Three Months Ended March 31,
   2022  2021
Research and development  $217,500   $278,815 
General and administrative   5,500    (1,153,575)
Total  $223,000   $(874,760)