Equity (Details 3) - USD ($)	12 Months Ended
Dec. 31, 2021	Dec. 31, 2020
Total	$ (173,163)	$ 4,206,252
Research and Development Expense [Member] \| Share-based Payment Arrangement, Option [Member]
Total	948,938	1,536,168
General and Administrative Expense [Member] \| Share-based Payment Arrangement, Option [Member]
Total	$ (1,122,101)	$ 2,670,084

Amount of cost expensed and capitalized for award under share-based payment arrangement.

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
-URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration