Equity (Tables)

12 Months Ended

Dec. 31, 2021

Equity [Abstract]

Schedule of warrants outstanding

	Shares of Common Stock Issuable for Warrants Outstanding as of				Weighted
	December 31,				Average
Description	2021		2020		Exercise Price		Expiration
Series E		-		584,416	$	1.54	September 8, 2021
Series F		7,246		7,246	$	3.45	February 23, 2022 & March 9, 2022
Series G		460,250		460,250	$	2.68	July 21, 2022
Series H		910,000		910,000	$	2.75	October 16, 2022
Series I		10,335,000		10,335,000	$	2.00	November 26, 2025
Total		11,712,496		12,296,912

Schedule of stock option activity

	Number of Options			Weighted Average Exercise Price ($)		Weighted Average Remaining Contractual Term (years)		Aggregate Intrinsic Value ($)
Outstanding at December 31, 2019		2,317,500			3.41
Granted		3,615,570			2.31
Forfeited		(37,500	)		4.20
Outstanding at December 31, 2020		5,895,570			2.45
Granted		50,000			1.72
Forfeited		(2,805,571	)		2.74
Outstanding at December 31, 2021		3,139,999			2.17		4.54		-
Vested and exercisable at December 31, 2021		2,639,999			1.99		4.48		-

Schedule of assumption of stock option activity

	Years Ended December 31,
	2021	2020
Risk-free interest rate	0.73%	0.21%	-	1.67%
Expected term in years	5.38	3.25	–	6.00
Weighted Avg. Expected Volatility	102.07	97.20%	–	110.71%
Expected dividend yield	0%		0%

Schedule of consolidated statement of operations

	Years Ended December 31,
	2021			2020
Research and development	$	948,938		$	1,536,168
General and administrative		(1,122,101	)		2,670,084
Total	$	(173,163	)	$	4,206,252