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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Cash flows from operating activities:      
Net loss $ (24,338,804) $ (20,658,846) $ (35,151,715)
Adjustments to reconcile net loss to net cash used in operating activities:      
Share-based compensation expense 2,519,750 3,658,874 2,624,742
Depreciation and amortization 1,860,682 1,569,848 1,224,217
Loss on disposal of equipment 261,814 167,097 39,983
Write-off of capitalized patent costs 0 31,501 0
Increase in inventory reserve 748,378 700,000 3,550,000
Amortization of premiums and discounts 12,225 10,313 20,036
Changes in operating assets and liabilities:      
Accounts receivable (1,137,543) (4,422,689) (2,478,494)
Inventories (350,943) (564,473) (2,948,873)
Prepaid expenses and other current assets 1,921,937 (934,356) (617,121)
Deferred costs (574,229) 714,704 (1,538,148)
Other assets 100,000 148,000 545,059
Accounts payable 2,858,884 (3,494,536) 2,688,054
Accrued expenses and other liabilities (582,295) 905,882 221,086
Deferred revenue 1,505,202 (6,030,160) 5,487,873
Net cash used in operating activities (15,194,942) (28,198,841) (26,333,301)
Cash flows from investing activities:      
Purchases of equipment, molds, furniture and fixtures (4,879,509) (5,643,043) (4,663,313)
Additions to patent rights (127,156) (1,043,628) (989,790)
Proceeds from maturities of investment securities 15,000,000 6,000,000 24,000,000
Purchases of investment securities   (15,037,675)  
Net cash provided by (used in) investing activities 9,993,335 (15,724,346) 18,346,897
Cash flows from financing activities:      
Proceeds from issuance of common stock, net   42,850,677  
Proceeds from exercise of stock options and warrants 101,092 30,800 3,105,102
Taxes paid related to net share settlement of equity awards (83,631) (87,770) (154,397)
Net cash provided by financing activities 17,461 42,793,707 2,950,705
Effect of exchange rate changes on cash 58 (733) (2,648)
Net decrease in cash and cash equivalents (5,184,088) (1,130,213) (5,038,347)
Cash and cash equivalents:      
Beginning of year 32,898,676 34,028,889 39,067,236
End of year 27,714,588 32,898,676 34,028,889
Supplemental disclosure of non-cash investing activities:      
Purchases of equipment, molds, furniture and fixtures recorded in accounts payable and accrued expenses 424,389 641,379 1,118,925
Additions to patent rights recorded in accounts payable and accrued expenses $ 44,589 $ 21,027 $ 949,631