Income Taxes - Schedule of Income (Loss) before Income Tax Domestic and Foreign (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Extraordinary Items, Noncontrolling Interest [Abstract]
Income (loss) before income taxes, US	$ (24,228,608)	$ (21,831,232)	$ (35,359,378)
Income (loss) before income taxes, Switzerland	(10,196)	1,347,386	232,663
Net loss before income taxes	$ (24,238,804)	$ (20,483,846)	$ (35,126,715)