X0303 4 2011-02-25 0 0001016169 ANTARES PHARMA, INC. AIS 0001054942 APPLE ROBERT F C/O ANTARES PHARMA, INC. 250 PHILLIPS BLVD, SUITE 290 EWING NJ 08618 0 1 0 0 Executive Vice President & CFO Common Stock 2011-02-25 4 A 0 34040 A 197920 D Represents grants of common stock, par value $0.01 per share, issued under the Antares Pharma, Inc. 2008 Equity Compensation Plan. 15,790 shares were granted based on achievement of a performance goal previously established and 18,250 shares were granted in lieu of cash as a partial bonus payment. Not applicable Robert F. Apple 2011-03-01