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Revenues, Significant Customers and Concentrations of Risk
12 Months Ended
Dec. 31, 2021
Revenue from Contract with Customer [Abstract]  
Revenues, Significant Customers and Concentrations of Risk Revenues, Significant Customers and Concentrations of Risk
We disaggregate our revenue by type of goods and services and customer location.
Years Ended December 31,
202120202019
Types of Goods and Services
Proprietary product sales, net$80,016 $62,878 $39,215 
Partnered product sales46,651 50,956 52,888 
Total product revenue, net126,667 113,834 92,103 
Licensing and development revenue19,623 14,466 7,529 
Royalties37,692 21,299 24,232 
Total revenue, net$183,982 $149,599 $123,864 
Customer Location
U.S.$178,290 $145,789 $120,231 
Europe5,692 3,810 3,463 
Other— — 170 
Total revenue, net$183,982 $149,599 $123,864 
Customers from which we derive 10% or more of our total revenue are as follows: 
Years Ended December 31,
202120202019
Teva42%40%41%
McKesson 1
13%12%10%
AmerisourceBergen Corporation 1
12%12%<10%
Cardinal Health 1
11%11%<10%
Covis<10%<10%20%
1     Revenue from sales to distributors, net of estimated sales returns and allowances based on shipments.