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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 F1IN2sx2E783bKGaERWj76pl7aP5iHN5tKB9murt61y6lVYrwr0GCGGUVfSuqS5j
 MF3/eaCMLrjVn1nsWDA4VA==

<SEC-DOCUMENT>0001016169-08-000045.txt : 20080516
<SEC-HEADER>0001016169-08-000045.hdr.sgml : 20080516
<ACCEPTANCE-DATETIME>20080516162904
ACCESSION NUMBER:		0001016169-08-000045
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080514
FILED AS OF DATE:		20080516
DATE AS OF CHANGE:		20080516

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ANTARES PHARMA, INC.
		CENTRAL INDEX KEY:			0001016169
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				411350192
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		250 PHILLIPS BLVD
		STREET 2:		SUITE 290
		CITY:			EWING
		STATE:			NJ
		ZIP:			08618
		BUSINESS PHONE:		609-359-3020

	MAIL ADDRESS:	
		STREET 1:		250 PHILLIPS BLVD
		STREET 2:		SUITE 290
		CITY:			EWING
		STATE:			NJ
		ZIP:			08618

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANTARES PHARMA INC
		DATE OF NAME CHANGE:	20060120

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANTARES PHARMA  INC
		DATE OF NAME CHANGE:	20020520

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANTARES PHARMA INC /MN/
		DATE OF NAME CHANGE:	20010604

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			APPLE ROBERT F
		CENTRAL INDEX KEY:			0001054942

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32302
		FILM NUMBER:		08842681

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		6102609364

	MAIL ADDRESS:	
		STREET 1:		C/O INKLINE PHARMACEUTICAL CO INC
		STREET 2:		SENTRY PARK EAST 1720 WALTON ROAD
		CITY:			BLUE BELL
		STATE:			PA
		ZIP:			19422
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>robertapple051508_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-05-14</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001016169</issuerCik>
        <issuerName>ANTARES PHARMA, INC.</issuerName>
        <issuerTradingSymbol>AIS</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001054942</rptOwnerCik>
            <rptOwnerName>APPLE ROBERT F</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ANTARES PHARMA, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>250 PHILLIPS BLVD, SUITE 290</rptOwnerStreet2>
            <rptOwnerCity>EWING</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08618</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Senior VP and CFO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-05-14</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>27500</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>72954</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>.85</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2008-05-14</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>82500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <value>2018-05-13</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>82500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>582500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Represents grant of shares of restricted Common Stock issued under the 2008 Equity Compensation Plan.  The shares vest in
 three equal annual installments.</footnote>
        <footnote id="F2">Not applicable.</footnote>
        <footnote id="F3">The option vests in equal quarterly installments over three years.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Robert F. Apple</signatureName>
        <signatureDate>2008-05-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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