X0202 3 2005-03-03 0 0001016006 CLOSURE MEDICAL CORP CLSR 0000200406 JOHNSON & JOHNSON 0 0 1 0 Common Stock, par value $0.01 per share 5055948 I See explanatory note below. Johnson & Johnson, a New Jersey Corporation, is party to a Stockholder Agreement dated as of March 3, 2005 with certain stockholders of Closure Medical Corporation (the "Stockholder Agreement). Pursuant to the Stockholder Agreement, Johnson & Johnson may be deemed a beneficial owner pursuant to Section 13(d) of the Securities Exchange Act of 1934, as amended (the "Act"), of 5,055,948 shares of common stock, par value $0.01 per share, of Closure Medical Corporation that are subject to the Stockholder Agreement (the "Shares"). Pursuant to Rule 16a-1(a)(4) under the Act, Johnson & Johnson hereby states that this Initial Statement of Beneficial Ownership of Securities on Form 3 shall not be deemed an admission that Johnson & Johnson is, for purposes of Section 16 of the Act or otherwise, the beneficial owner of any equity securities of Closure Medical Corporation. Johnson & Johnson has no pecuniary interest in the Shares. Michael H. Ullmann 2005-03-09