SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* Boxer Capital, LLC (Last) (First) (Middle) 11682 EL CAMINO REAL, SUITE 320 (Street) SAN DIEGO CA 92130 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol Mirati Therapeutics, Inc. [ MRTX ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 10/03/2017
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	10/03/2017		X		189,780	A	$7.86	1,227,774	D(1)
Common Stock	10/03/2017		X		78,186	A	$7.86	513,630	D(2)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Warrant (right to purchase)	$7.86	10/03/2017		X			189,780	11/21/2012	11/21/2017	Common Stock	189,780	$0.00	0	D
Warrant (right to purchase)	$7.86	10/03/2017		X			78,186	11/21/2012	11/21/2017	Common Stock	78,186	$0.00	0	D

1. Name and Address of Reporting Person* Boxer Capital, LLC (Last) (First) (Middle) 11682 EL CAMINO REAL, SUITE 320 (Street) SAN DIEGO CA 92130 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Braslyn Ltd. (Last) (First) (Middle) CAY HOUSE, EP TAYLOR DRIVE (Street) LYFORD CAY, NEW PROVIDENCE C5 N7776 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* LEWIS JOSEPH (Last) (First) (Middle) C/O CAY HOUSE P.O. BOX N-7776 E.P. TAYLOR DRIVE LYFORD CAY (Street) NEW PROVIDENCE C5 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Fuglesang Christopher (Last) (First) (Middle) 11682 EL CAMINO REAL, SUITE 320 (Street) SAN DIEGO CA 92130 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* LAPPE RODNEY W (Last) (First) (Middle) 4660 LA JOLLA VILLAGE DRIVE, SUITE 500 (Street) SAN DIEGO CA 92121 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer X Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* LIEBERBURG IVAN M (Last) (First) (Middle) 11682 EL CAMINO REAL, SUITE 320 (Street) SAN DIEGO CA 92130 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Reisman Neil (Last) (First) (Middle) 11682 EL CAMINO REAL, SUITE 320 (Street) SAN DIEGO CA 92130 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer X Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Dissanayake Shehan Bharatha (Last) (First) (Middle) 11682 EL CAMINO REAL, SUITE 320 (Street) SAN DIEGO CA 92130 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Davis Aaron I. (Last) (First) (Middle) 11682 EL CAMINO REAL, SUITE 320 (Street) SAN DIEGO CA 92130 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* MVA Investors, LLC (Last) (First) (Middle) 11682 EL CAMINO REAL, SUITE 320 (Street) SAN DIEGO CA 92130 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. These securities are owned directly by Boxer Capital, LLC ("Boxer Capital"), which may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, (ii) Boxer Asset Management Inc., (iii) MVA Investors, LLC ("MVA Investors"), (iv) Braslyn Ltd., (v) Joe Lewis, (vi) Christopher Fuglesang, (vii) Rodney W. Lappe, (viii) Ivan M. Lieberburg, (ix) Neil Reisman, (x) Shehan B. Dissanayake, and (xi) Aaron I. Davis (collectively, the "Boxer Group"). Joseph C. Lewis is the sole indirect beneficial owner of and controls Braslyn Ltd.

2. These securities are owned directly and solely by MVA Investors, which has sole voting and dispositive power with respect to these securities. Each of Messrs. Fuglesang, Lieberburg, Reisman, Dissanayake and Davis is a member of MVA Investors. Each member of the Boxer Group other than MVA Investors disclaims beneficial ownership of these securities to the extent it or he does not have a pecuniary interest therein.

Remarks:

Form 1 of 2 Because the number of Reporting Persons exceeds the Form 4 limit, additional Reporting Persons are included on another Form 4 filed on the same date.

	Boxer Capital, LLC, By: /s/ Aaron I Davis, Aaron I. Davis	10/03/2017
	MVA Investors, LLC, By: /s/ Aaron I. Davis, Aaron I. Davis	10/03/2017
	Braslyn Ltd., By: /s/ Jason Callender, Jason Callender	10/03/2017
	Joseph C. Lewis, By: /s/ Joseph C. Lewis, Joseph C. Lewis	10/03/2017
	Christopher Fuglesang, By: /s/ Christopher Fuglesang, Christopher Fuglesang	10/03/2017
	Rodney W. Lappe, By: /s/ Rodney W. Lappe, Rodney W. Lappe	10/03/2017
	Ivan M. Lieberburg, By: /s/ Ivan M. Lieberburg, Ivan M. Lieberburg	10/03/2017
	Neil Reisman, By: /s/ Neil Reisman, Neil Reisman	10/03/2017
	Shehan B. Dissanayake, By: /s/ Shehan B. Dissanayake, Shehan B. Dissanayake	10/03/2017
	Aaron I. Davis, By: /s/ Aaron I. Davis, Aaron I. Davis	10/03/2017
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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