-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 Kf1wHmKcwxgaD8PW0yfd/UVzSagGyG5pHQNNEbyJdUVXCMa8cIroiZzMYQEULZDy
 Ykgo+kxswI9aTa2w8km6vQ==

<SEC-DOCUMENT>0001209191-08-026897.txt : 20080501
<SEC-HEADER>0001209191-08-026897.hdr.sgml : 20080501
<ACCEPTANCE-DATETIME>20080501171756
ACCESSION NUMBER:		0001209191-08-026897
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080429
FILED AS OF DATE:		20080501
DATE AS OF CHANGE:		20080501

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BioScrip, Inc.
		CENTRAL INDEX KEY:			0001014739
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-DRUG STORES AND PROPRIETARY STORES [5912]
		IRS NUMBER:				050489664
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		100 CLEARBROOK ROAD
		CITY:			ELMSFORD
		STATE:			NY
		ZIP:			10523
		BUSINESS PHONE:		914 460 1600

	MAIL ADDRESS:	
		STREET 1:		100 CLEARBROOK ROAD
		CITY:			ELMSFORD
		STATE:			NY
		ZIP:			10523

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MIM CORP
		DATE OF NAME CHANGE:	19960516

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Ordemann Thomas
		CENTRAL INDEX KEY:			0001430965

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-28740
		FILM NUMBER:		08795672

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		914-460-1623

	MAIL ADDRESS:	
		STREET 1:		C/O BIOSCRIP, INC.
		STREET 2:		100 CLEARBROOK ROAD
		CITY:			ELMSFORD
		STATE:			X1
		ZIP:			10523
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>bny57085_bny3to.xml
<DESCRIPTION>MAIN DOCUMENT DESCRIPTION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2008-04-29</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001014739</issuerCik>
        <issuerName>BioScrip, Inc.</issuerName>
        <issuerTradingSymbol>BIOS</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001430965</rptOwnerCik>
            <rptOwnerName>Ordemann Thomas</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>100 CLEARBROOK ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ELMSFORD</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10523</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Executive Vice President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, $.0001 par value</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>46063.00</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Option to Purchase Common Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>5.46</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2008-08-01</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2017-08-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock, $.0001 par value</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>80000.00</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Option to Purchase Common Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>6.52</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2009-04-29</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2018-04-29</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock, $.0001 par value</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>50625.00</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Vests and becomes exercisable in three equal annual installments commencing on the first anniversary of the date of grant.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Thomas Ordemann</signatureName>
        <signatureDate>2008-05-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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