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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Statement [Abstract]      
Revenue $ 143,370 $ 156,473 $ 181,157
Cost of goods sold 52,284 64,550 59,828
Gross profit 91,086 91,923 121,329
Operating expenses:      
Research and development 18,104 20,793 21,019
Clinical and regulatory affairs 14,036 13,851 12,952
Marketing and sales 64,673 76,855 92,400
General and administrative 35,984 43,477 35,301
Restructuring costs 838 3,270 1,477
Contract termination, product withdrawal and business acquisition expenses 0 1,869 0
Total operating expenses 133,635 160,115 163,149
Loss from operations (42,549) (68,192) (41,820)
Other income (expense):      
Interest income 6 10 83
Interest expense (34,973) (27,658) (22,064)
Change in fair value of contingent consideration related to acquisition 1,700 7,100 2,900
Loss on debt extinguishment (11,756) (2,270) (6,512)
Change in fair value of derivative liabilities 17,713 12,097 0
Other (expense) income, net 377 (517) 554
Total other expense, net (26,933) (11,238) (25,039)
Net loss before income taxes (69,482) (79,430) (66,859)
Income tax (expense) benefit 4,725 (284) 459
Net loss (64,757) (79,714) (66,400)
Comprehensive loss, net of taxes:      
Net loss (64,757) (79,714) (66,400)
Other comprehensive (loss) income on foreign currency translation (772) (747) 1,847
Comprehensive loss $ (65,529) $ (80,461) $ (64,553)
Basic and diluted net loss per share (in USD per share) $ (3.84) $ (9.07) $ (7.97)
Shares used in computing basic and diluted net loss per share (in shares) 16,850 8,790 8,333