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Net Loss Per Share (Details) - shares
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]        
Outstanding securities used in calculations (in shares) 1,589,715,000 738,093,000 1,557,513,000 730,485,000
Conversion features under term loan facility        
Potential Dilutive Effect of Securities [Abstract]        
Conversion of Deerfield Warrants (in shares)     11,996,038 0
Common stock options        
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]        
Outstanding securities used in calculations (in shares) 0 21,290,000 0 25,161,000
Restricted stock awards        
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]        
Outstanding securities used in calculations (in shares) 3,579,000 12,599,000 3,107,000 12,235,000
Restricted stock units        
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]        
Outstanding securities used in calculations (in shares) 64,134,000 57,203,000 32,404,000 46,088,000
Warrants        
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]        
Outstanding securities used in calculations (in shares) 1,522,002,000 647,001,000 1,522,002,000 647,001,000
Convertible notes        
Potential Dilutive Effect of Securities [Abstract]        
Conversion of the Notes (in shares)     8,463,236 1,193,938