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Contingently Issuable Common Stock (Details) - USD ($)
$ / shares in Units, $ in Thousands, shares in Millions
3 Months Ended 9 Months Ended
Dec. 10, 2010
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Fair Value of Contingently Issuable Common Stock          
Beginning balance       $ 9,300  
Fair Value Adjustment of Contingent Payment for the nine months ended September 30, 2018   $ (5,000) $ (800) (4,300) $ (3,400)
Ending balance   5,000   5,000  
Nelix Milestones          
Business Acquisition [Line Items]          
Number of shares contingently issuable (in shares) 10.2        
Estimated fair value of contingent payment $ 28,200        
PMA Milestone          
Business Acquisition [Line Items]          
Common shares value   $ 15,000   $ 15,000  
Number of shares contingently issuable (in shares)       3.3  
Share price (in dollars per share)   $ 4.5   $ 4.5  
Closing stock price (in dollars per share)   $ 1.91   $ 1.91  
Average daily closing stock price       30 days  
Days prior to milestone achievement announcement       5 days  
Contingent consideration, at fair value hypothetical value   $ 6,400   $ 6,400  
Nellix          
Business Acquisition [Line Items]          
Purchase price common shares (in shares) 3.2        
Common shares value $ 19,400