ENDOLOGIX, INC.

2 Musick

Irvine, California 92618

July 17, 2018

SUBMITTED VIA EDGAR

Ms. Amanda Ravitz

Ms. Heather Percival

Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Re:    Endologix, Inc. Acceleration Request

Registration Statement on Form S-3 (File No. 333- 225320)

Requested Date:    July 19, 2018

Requested Time:    5:00 P.M. Eastern Time

Dear Ms. Ravitz and Ms. Percival:

Pursuant to Rule 461 of the Securities Act of 1933, as amended (the “Securities Act”), Endologix, Inc., a Delaware corporation (the “Company”), hereby respectfully requests that the Securities and Exchange Commission (the “Commission”) take appropriate action to declare the above-captioned Registration Statement on Form S-3 effective at the “Requested Date” and “Requested Time” set forth above, or as soon thereafter as practicable.

Should the Commission have any questions regarding this acceleration request, please do not hesitate to contact Ryan C. Wilkins, an attorney with the Company’s outside legal counsel, Stradling Yocca Carlson & Rauth, P.C., via telephone at (949) 725-4115 or via email at rwilkins@sycr.com.

Sincerely,

ENDOLOGIX, INC.

/s/ Jeremy Hayden

Jeremy Hayden

General Counsel

cc:

Endologix, Inc.

Vaseem Mahboob, Chief Financial Officer

Stradling Yocca Carlson & Rauth, P.C.

Ryan C. Wilkins, Esq.