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Contingently Issuable Common Stock (Details) - USD ($)
$ / shares in Units, $ in Thousands, shares in Millions
3 Months Ended
Dec. 10, 2010
Mar. 31, 2018
Mar. 31, 2017
Fair Value of Contingently Issuable Common Stock      
Beginning balance   $ 9,300  
Fair Value Adjustment of Contingent Payment for the three months ended March 31, 2018   (1,100) $ 1,200
Ending balance   8,200  
Nelix Milestones      
Business Acquisition [Line Items]      
Number of shares contingently issuable (in shares) 10.2    
Estimated fair value of contingent payment $ 28,200    
PMA Milestone      
Business Acquisition [Line Items]      
Common shares value   $ 15,000  
Number of shares contingently issuable (in shares)   3.3  
Share price (in dollars per share)   $ 4.5  
Closing stock price (in dollars per share)   $ 4.23  
Average daily closing stock price   30 days  
Days prior to milestone achievement announcement   5 days  
Contingent consideration, at fair value hypothetical value   $ 14,100  
Nellix      
Business Acquisition [Line Items]      
Purchase price common shares (in shares) 3.2    
Common shares value $ 19,400