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Net Loss Per Share (Details) - USD ($)
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Apr. 03, 2017
Nov. 30, 2015
Nov. 02, 2015
Dec. 10, 2013
Earnings Per Share, Basic and Diluted [Abstract]            
Net loss $ (19,767,000) $ (21,314,000)        
Shares used in computing basic and diluted net loss per share (in shares) 83,706,000 82,928,000        
Basic and diluted net loss per share (in dollars per share) $ (0.24) $ (0.26)        
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]            
Outstanding securities used in calculations (in shares) 695,000 1,068,000        
Potential Dilutive Effect of Securities [Abstract]            
Conversion of the Notes (in shares) 11,939,000 14,767,000        
Conversion of Deerfield Warrants (in shares) 6,470,000 0        
Facility Agreement | Deerfield Warrants | Common Stock            
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]            
Warrants issued (in shares)     6,470,000      
Exercise price of warrants issued (in dollars per share)     $ 9.23      
Convertible Debt | 2.25% Convertible Senior Notes            
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]            
Convertible notes $ 17,600,000         $ 86,300,000
Stated interest rate 2.25%         2.25%
Debt instrument face amount           $ 86,250,000
Convertible Debt | 3.25% Convertible Senior Notes            
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]            
Convertible notes $ 109,400,000     $ 125,000,000    
Stated interest rate         3.25%  
Debt instrument face amount         $ 125,000,000.0  
Secured Debt | Facility Agreement            
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]            
Stated interest rate 6.87%          
Debt instrument face amount     $ 120,000,000.0      
Common stock options            
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]            
Outstanding securities used in calculations (in shares) 270,000 696,000        
Restricted stock awards            
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]            
Outstanding securities used in calculations (in shares) 118,000 120,000        
Restricted stock units            
Securities Excluded from Calculations of Earnings Per Share Because Impact Would Have Been Anti-Dilutive [Abstract]            
Outstanding securities used in calculations (in shares) 307,000 252,000