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Income Tax Expense (Income Tax Benefit Computation) (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Tax Disclosure [Abstract]      
Income tax benefit at federal statutory rate $ (22,732) $ (52,418) $ (20,315)
State income tax benefit, net of federal benefit (1,114) (2,323) (937)
Meals and entertainment 454 445 328
Research and development credits (913) (2,041) (1,756)
Stock-based compensation 3,203 2,604 1,633
Derivative loss 0 14,903 0
Contingent consideration (986) (850) 34
Foreign tax rate differential 692 1,394 1,013
Net change in valuation allowance (24,976) 35,678 10,052
Return to provision true-up 5,719 1,981 583
Unrecognized tax benefits 457 971 928
Federal tax rate change 39,807 0 0
Other, net (70) 154 (900)
Income tax expense (benefit) $ (459) $ 498 $ (9,337)