Commitments and Contingencies (Details) $ in Thousands				12 Months Ended
	Mar. 17, 2016 USD ($)	Feb. 01, 2014	Jun. 12, 2013 USD ($) ft² facility option	Dec. 31, 2017 USD ($)	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)
Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract]
2018				$ 3,450
2019				3,567
2020				3,735
2021				3,692
2022				3,800
2023 and thereafter				18,021
Total				36,265
Rent expense				$ 3,400	$ 3,300	$ 2,300
Number of facilities | facility			2
Operating Leased Assets [Line Items]
Term of contract			15 years
Number of renewal options | option			1
Renewal term			5 years
Minimum rentals			$ 1,900
Operating Leases, Future Minimum Payments Due, Base Rent Increases [Abstract]
2015				3.00%
2016				3.00%
2017				3.00%
2018				3.00%
2019				3.00%
2020 and beyond				4.00%
Abatement period			9 months
Landlord improvement allowance			$ 6,800
Optional lease renewal period			5 years
Litigation settlement, amount	$ 4,700
Loss on contract termination					$ 2,500
Office, Research and Development and Manufacturing Facilities
Operating Leased Assets [Line Items]
Facility, area | ft²			129,000
Administrative Office
Operating Leased Assets [Line Items]
Facility, area | ft²			2,900
Manufacturing Facility
Operating Leased Assets [Line Items]
Facility, area | ft²			110,000
Minimum
Operating Leases, Future Minimum Payments Due, Base Rent Increases [Abstract]
Severance payment, period, prior to change in control		6 months
Severance payment, period, following change in control		18 months
Maximum
Operating Leases, Future Minimum Payments Due, Base Rent Increases [Abstract]
Severance payment, period, prior to change in control		18 months
Severance payment, period, following change in control		24 months