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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2016
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Summary of Stock-based Compensation Recognized, Common Stock Purchased, and Average Price
The table below summarizes the stock-based compensation recognized, common stock shares purchased by Company employees, and the average purchase price per share as part of the ESPP program during the years ended December 31, 2016, 2015, and 2014.
 
Year Ended December 31,
 
2016
 
2015
 
2014
Stock-based compensation expense
$
1,205


$
921


$
841

Common stock shares purchased by Company employees
394,120


355,557


254,602

Average purchase price per share
$
8.17


$
8.33


$
10.26

Schedule of Compensation Expense Included in COGS and Operating Expenses
Stock-based compensation expense included in cost of goods sold and operating expenses for years ended December 31, 2016, 2015, and 2014 was as follows:

Year Ended December 31,

2016

2015

2014
Cost of goods sold
$
944


$
1,000


$
857

Operating expenses:








Research and development
1,528


1,005


770

Clinical and regulatory affairs
672


858


644

Marketing and sales
4,335


3,237


2,533

General and administrative
4,807


3,155


3,063

Total operating expenses
$
11,342


$
8,255


$
7,010










Total
$
12,286


$
9,255


$
7,867

Schedule of Fair Value Assumptions of Stock Options Granted
The fair value of stock options granted was estimated at the date of grant using the Black-Scholes option-pricing model. The following assumptions were used to determine fair value for the stock awards granted in the applicable year:

Year Ended December 31,

2016

2015

2014
Average expected option life (in years) (a)
5.5

5.5

5.5
Volatility (b)
44.2%

43.3%

54.0%
Risk-free interest rate (c)
1.2%

1.6%

1.8%
Dividend Yield (d)
—%

—%

—%
Weighted-average grant-date fair value per stock option
$3.45

$6.37

$6.22
(a) Determined by the historical stock option exercise behavior of the Company's employees (maximum term is 10 years).
(b) Measured using daily price observations for a period equal to stock options' expected term.
(c) Based upon the United States Treasury yields in effect (for a period equaling the stock options' expected term).
(d) The Company has never paid cash dividends on its common stock and does not expect to declare any cash dividends.
Schedule of Stock Option Activity
Stock option activity during the year ended December 31, 2016 is as follows:
 
Number of
Stock Options

Weighted
Average
Exercise Price

Weighted-
Average
Remaining
Contractual
Life (Years)

Aggregate Intrinsic Value
Outstanding — January 1, 2016
5,973,049

10.42





Granted
4,381,500

7.94





Exercised
(524,504)

5.96


(a)
$
2,656

Forfeited
(810,051)

11.16





Expired
(346,779)

13.99





Outstanding — December 31, 2016
8,673,215

$9.22

6.7
(b)
$
3,247

Vested and Expected to Vest — December 31, 2016
7,906,267

9.17

6.5
(b)
$
3,247

Vested — December 31, 2016
3,788,707

8.58

4.5
(b)
$
3,247


(a) Represents the total difference between the Company's stock price at the time of exercise and the stock option exercise price, multiplied by the number of options exercised.
(b) Represents the total difference between the Company's closing stock price on the last trading day of period reported on and the stock option exercise price, multiplied by the number of in-the-money options as of the period reported on. The amount of intrinsic value will change based on the fair market value of the Company's stock.
Schedule of Outstanding Stock Option Grants
The following table summarizes information regarding outstanding stock option grants as of December 31, 2016:
 
 
Outstanding

Exercisable
Range of Exercise Prices
 
Granted
Stock Options
Outstanding

Weighted-
Average
Remaining
Contractual
Life (Years)

Weighted-
Average
Exercise
Price

Granted
Stock Options
Exercisable

Weighted-
Average
Exercise
Price
$
1.64

$
6.91

 
1,756,509

2.9

$
3.99


1,584,707

$
3.69

7.00

7.25

 
1,032,575

8.4

7.23


240,149

7.21

7.26

7.53

 
2,140,066

8.5

7.53


186,917

7.50

7.57

13.17

 
1,809,080

6.8

11.17


849,003

11.39

13.21

17.60

 
1,934,985

7.0

15.08


927,931

14.94

$
1.64

$
17.60

 
8,673,215

6.7

$
9.22


3,788,707

$
8.58

Summary of Activity and Related Information for Restricted Stock Awards
The following table summarizes activity and related information for the Company's restricted stock awards:

Number of
Restricted Stock Awards(2)

Weighted Average
Fair
Value per Share at Grant Date

Grant Date Fair Value

Vest Date Fair Value(1)
Unvested as of December 31, 2015
885,060


$
13.45







Granted
758,128


8.29


$
6,285




Forfeited
(87,231
)

14.45







Vested
(245,938
)

14.29





$
2,608

Unvested as of December 31, 2016
1,310,019


$
10.24







(1) Represents the Company's stock price on the vesting date multiplied by the number of vested shares.
(2) Shares granted in 2016 include 233,482 performance stock units that have certain performance conditions required to be achieved to vest.