Contingently Issuable Common Stock (Details) - USD ($) $ / shares in Units, $ in Thousands, shares in Millions			3 Months Ended
	Jun. 17, 2014	Dec. 10, 2010	Mar. 31, 2016	Mar. 31, 2015	Jun. 16, 2014
Fair Value of Contingently Issuable Common Stock [Roll Forward]
Beginning balance			$ 14,700
Fair Value Adjustment of Contingent Payment for the three months ended March 31, 2016			0	$ 100
Ending balance			14,700
Nelix Milestones
Business Acquisition [Line Items]
Number of shares contingently issuable (in shares)		10.2
Estimated fair value of contingent payment		$ 28,200
OUS Milestone
Business Acquisition [Line Items]
Purchase price common shares (in shares)	2.7
OUS Milestone | Common Stock
Business Acquisition [Line Items]
Contingent consideration, liability, value, low			10,000
Contingent consideration, liability, value, high			$ 24,000
Contingent consideration, liability, shares, high (in shares)			6.9
Contingent consideration, liability, shares, low (in shares)			1.3
OUS Milestone | Common Stock | Minimum
Business Acquisition [Line Items]
Share price (in dollars per share)					$ 3.50
OUS Milestone | Common Stock | Maximum
Business Acquisition [Line Items]
Share price (in dollars per share)					$ 7.50
PMA Milestone
Business Acquisition [Line Items]
Common shares value		$ 15,000
Number of shares contingently issuable (in shares)			1.8
Closing stock price (in dollars per share)			$ 8.36
Contingent consideration, at fair value hypothetical value			$ 15,200
PMA Milestone | Minimum
Business Acquisition [Line Items]
Share price (in dollars per share)		$ 4.5
Nellix
Business Acquisition [Line Items]
Purchase price common shares (in shares)		3.2
Common shares value		$ 19,400